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CAS 309-36-4

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Methohexital sodium

Description:
Methohexital sodium is a short-acting barbiturate anesthetic primarily used for induction of anesthesia and sedation. It is a white to off-white crystalline powder that is soluble in water, making it suitable for intravenous administration. The compound acts as a central nervous system depressant, enhancing the effects of gamma-aminobutyric acid (GABA) at the GABA-A receptor, which leads to sedation and hypnosis. Methohexital sodium has a rapid onset of action, typically within minutes, and a relatively short duration of effect, which makes it advantageous for procedures requiring quick recovery. It is important to note that, like other barbiturates, methohexital sodium carries a risk of respiratory depression and potential for abuse. Its use is generally restricted to controlled medical settings, and it is classified as a Schedule IV controlled substance in many jurisdictions. Proper dosing and monitoring are essential to minimize adverse effects and ensure patient safety during its administration.
Formula:C14H18N2O3·Na
InChI:InChI=1S/C14H18N2O3.Na/c1-5-7-8-10(3)14(9-6-2)11(17)15-13(19)16(4)12(14)18;/h6,10H,2,5,9H2,1,3-4H3,(H,15,17,19);
InChI key:InChIKey=ZNCHEYWRDOJPAW-UHFFFAOYSA-N
SMILES:C(C#CCC)(C)C1(CC=C)C(=O)N(C)C(=O)NC1=O.[Na]
Synonyms:
  • 1-Methyl-5-allyl-5-(1-methyl-2-pentynyl)barbituric acid sodium salt
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-methyl-5-(1-methyl-2-pentyn-1-yl)-5-(2-propen-1-yl)-, sodium salt (1:1)
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-methyl-5-(1-methyl-2-pentynyl)-5-(2-propenyl)-, (+-)-, monosodium salt
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-methyl-5-(1-methyl-2-pentynyl)-5-(2-propenyl)-, sodium salt
  • 5-Allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid sodium salt
  • Barbituric acid, 5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-, sodium deriv.
  • Barbituric acid, 5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-, sodium salt
  • Brevimytal
  • Brevimytal sodium
  • Brevital
  • See more synonyms
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  • Methohexital sodium
    Biosynth
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    Methohexital sodium

    Controlled Product
    CAS:
    Methohexital is a potent tumor inhibitor that has been shown to induce apoptosis in human and Chinese hamster ovary cells. It is excreted primarily in urine and has been found to inhibit chitin synthase activity, which may contribute to its anticancer properties. Methohexital also acts as a potassium channel blocker and kinase inhibitor, which may further contribute to its anticancer effects. This drug has been studied extensively for its potential use in the treatment of various types of cancer, including breast and lung cancers. Additionally, Methohexital has been found to have heparin-like properties, which may be useful in preventing blood clots associated with cancer.
    Formula:C14H17N2NaO3
    Purity:Min. 95%
    Molecular weight:284.29 g/mol

    Ref: 3D-AAA30936

    500mg
    827.00€
    1g
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