CAS 3092659-72-5

Formula: C54H56FN9O6

InChI: InChI=1S/C54H56FN9O6/c1-29-21-37(22-30(2)43(29)55)64-45(61-19-18-60(50(61)68)36-10-11-38-40(25-36)59(7)48(66)53(38)14-8-15-53)42-32(4)62(28-52(16-17-52)44(42)57-64)46(65)41-24-35-23-33(34-13-20-69-51(5,6)27-34)9-12-39(35)63(41)54(26-31(54)3)47-56-49(67)70-58-47/h9-12,18-19,21-25,31-32,34H,8,13-17,20,26-28H2,1-7H3,(H,56,58,67)/t31-,32-,34-,54-/m0/s1

InChI key: AQIDBUCFPVEBIJ-UYDHTGFJSA-N

SMILES: C[C@H]1C[C@]1(C2=NOC(=O)N2)N3C4=C(C=C(C=C4)[C@H]5CCOC(C5)(C)C)C=C3C(=O)N6CC7(CC7)C8=NN(C(=C8[C@@H]6C)N9C=CN(C9=O)C1=CC2=C(C=C1)C1(CCC1)C(=O)N2C)C1=CC(=C(C(=C1)C)F)C

3-((1S,2S)-1-(5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-2'-(4-fluoro-3,5-dimethylphenyl)-4'-methyl-3'-(3-(1'-methyl-2'-oxospiro[cyclobutane-1,3'-indolin]-6'-yl)-2-oxo-2,3-dihydro-1H-imidazol

CAS: 3092659-72-5

3-((1S,2S)-1-(5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-2'-(4-fluoro-3,5-dimethylphenyl)-4'-methyl-3'-(3-(1'-methyl-2'-oxospiro[cyclobutane-1,3'-indolin]-6'-yl)-2-oxo-2,3-dihydro-1H-imidazol

Formula: C₅₄H₅₆FN₉O₆

Purity: 95%

Molecular weight: 946.08

Ref: 54-PC1041549

GLP-1R-agonist-43

CAS: 3092659-72-5

GLP-1R-agonist-43 (Compound A) is an orally active GLP-1R agonist with an EC₅₀ of 2.68 nM. It is useful in research related to non-insulin-dependent diabetes (type 2 diabetes) and obesity.

Formula: C₅₄H₅₆FN₉O₆

Molecular weight: 946.08

Ref: TM-T218926

3-((1S,2S)-1-(5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-2'-(4-fluoro-3,5-dimethylphenyl)-4'-methyl-3'-(3-(1'-methyl-2'-oxospiro[cyclobutane-1,3'-indolin]-6'-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2',4',5',6'-tetrahydrospiro[cyclopropane-1,7'-py

CAS: 3092659-72-5

Formula: C₅₄H₅₆FN₉O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 946.0775

Ref: IN-DA0IKHZ9