CAS 3101563-06-5

Formula: C23H15ClF2N6O2

InChI: InChI=1S/C23H15ClF2N6O2/c1-2-22(33)31-10-17-18(11-31)32(20-4-5-27-12-29-20)23(30-17)14-8-19(16(26)9-15(14)25)34-21-7-13(24)3-6-28-21/h2-9,12H,1,10-11H2

InChI key: RRLVWYDNIVCNDY-UHFFFAOYSA-N

SMILES: C=CC(=O)N1CC2=C(C1)N(C(=N2)C3=CC(=C(C=C3F)F)OC4=NC=CC(=C4)Cl)C5=NC=NC=C5

AZ14240475

CAS: 3101563-06-5

AZ14240475 is a potent, selective, brain-penetrant inhibitor of EGFREx20Ins mutants (EGFREx20Ins mutants) with a pIC₅₀ of 7.6, playing a significant role in cancer research.

Formula: C₂₃H₁₅ClF₂N₆O₂

Color and Shape: Solid

Molecular weight: 480.854

Ref: TM-T204475