CAS 3105969-02-3

Formula: C24H31N5O5S

InChI: InChI=1S/C24H31N5O5S/c1-15-14-25-23(27-17-12-19(32-5)21(34-7)20(13-17)33-6)28-22(15)26-16-9-8-10-18(11-16)35(30,31)29-24(2,3)4/h8-14,29H,1-7H3,(H2,25,26,27,28)

InChI key: KEGVORHWJANDMS-UHFFFAOYSA-N

SMILES: CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC(=C(C(=C3)OC)OC)OC

TG101209 analog 1

CAS: 3105969-02-3

TG101209 analog 1 (Compound 8h) serves as an inhibitor of BUB1B, exhibiting an IC50 of 10.36 μM. It also possesses cytotoxic properties, demonstrated by an IC50 of 1.347 μM against Caki-1 cells, and can induce necrosis and apoptosis.

Formula: C₂₄H₃₁N₅O₅S

Color and Shape: Solid

Molecular weight: 501.598

Ref: TM-T204153