CAS 3109321-90-3
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TYMJ-01
CAS:TYMJ-01 is a fluorescent probe and an eEF2K degrader. It induces specific, dose-dependent degradation of eEF2K through the ubiquitin-proteasome pathway with a DC50 of 82 nM. TYMJ-01 inhibits the proliferation, migration, and invasion of triple-negative breast cancer cells and enables dynamic fluorescent imaging of eEF2K degradation within these cells. Additionally, it enhances the antitumor activity of Paclitaxel. TYMJ-01 is applicable for research on triple-negative breast cancer.Formula:C27H28N6O4SMolecular weight:532.61
