CAS 3109982-48-8

SGK1-IN-8

CAS: 3109982-48-8

SGK1-IN-8 (compound 55) is an inhibitor of SGK1 and GSK3β, exhibiting an IC50 of 0.11 μM for human SGK1 and 3.39 μM for human GSK3β. It reduces the catalytic activity of both SGK1 and GSK3β and decreases the phosphorylation level of TAU protein at the Ser214 site. SGK1-IN-8 is applicable in Alzheimer's disease research.

Formula: C₁₈H₁₃ClN₄O

Molecular weight: 336.78

Ref: TM-T219117