CAS 3110703-72-2

TYD-68

CAS: 3110703-72-2

TYD-68 is a potent and selective CRBN-recruiting TYK2 PROTAC degrader, with a DC₅₀ value of 0.42 nM. This compound effectively inhibits IL-12 and IFN-α-induced phosphorylation of STAT4 and STAT1, thereby blocking TYK2-dependent signaling pathways. TYD-68 is applicable in psoriasis research.

Formula: C₄₃H₄₀FN₁₁O₇

Color and Shape: Odour Solid

Molecular weight: 841.85

Ref: TM-T206972