CAS 3114652-09-1

Formula: C16H17ClN6OS

InChI: InChI=1S/C16H17ClN6OS/c1-16(2,3)14(24)23-15(20-8-10-4-5-12(17)25-10)21-13(22-23)11-9-18-6-7-19-11/h4-7,9H,8H2,1-3H3,(H,20,21,22)

InChI key: IKHTURDVCDPXHC-UHFFFAOYSA-N

SMILES: CC(C)(C)C(=O)N1C(=NC(=N1)C2=NC=CN=C2)NCC3=CC=C(S3)Cl

Thrombin inhibitor 13

CAS: 3114652-09-1

Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.

Formula: C₁₆H₁₇ClN₆OS

Color and Shape: Solid

Molecular weight: 376.864

Ref: TM-T204110