CAS 312271-03-7

Formula: C19H24N4O4S

InChI: InChI=1S/C19H24N4O4S/c1-11(2)9-22(10-12(3)4)15-6-5-13(8-16(15)23(26)27)7-14-17(24)20-19(28)21-18(14)25/h5-8,11-12H,9-10H2,1-4H3,(H2,20,21,24,25,28)

InChI key: BWEKPQUKWLNUKX-UHFFFAOYSA-N

SMILES: CC(C)CN(CC(C)C)C1=C(C=C(C=C1)C=C2C(=O)NC(=S)NC2=O)[N+](=O)[O-]

M2I-1

CAS: 312271-03-7

M2I-1

Formula: C₁₉H₂₄N₄O₄S

Purity: ≥95%

Molecular weight: 404.48

Ref: 54-BUP10035

M2I-1

CAS: 312271-03-7

Formula: C₁₉H₂₄N₄O₄S

Purity: 98%

Molecular weight: 404.4833

Ref: IN-DA00BF7M

M2I-1

CAS: 312271-03-7

M2I-1 inhibits Mad2 binding to Cdc20, disrupting SAC-related PPI and Mad2 dynamics, blocks Mad2-F-Mbp1 in FP assays.

Formula: C₁₉H₂₄N₄O₄S

Purity: 99.02% - >99.99%

Color and Shape: Red Solid

Molecular weight: 404.483

Ref: TM-T4647

M2I-1

CAS: 312271-03-7

5-(4-(Diisobutylamino)-3-nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Formula: C₁₉H₂₄N₄O₄S

Purity: 98%

Molecular weight: 404.48

Ref: IN-DG630633

M2I-1

CAS: 312271-03-7

M2I-1 is a molecule that has been shown to cause death in vitro. M2I-1 interacts with the pro-apoptotic protein Bax, which leads to the activation of caspase and apoptosis. The interaction of M2I-1 with Bax prevents the inhibition of mitotic checkpoint and induces cell death through programmed cell death. In cancer cells, M2I-1 can induce cell death by inhibiting the activity of chk1. It has also been shown to have an inhibitory effect on nocodazole-induced mitotic arrest.

Formula: C₁₉H₂₄N₄O₄S

Purity: Min. 95%

Molecular weight: 404.48 g/mol

Ref: 3D-MMA27103