CAS 31252-85-4

p-Nitrophenyl iodoacetate

Description:

p-Nitrophenyl iodoacetate is an organic compound characterized by its structure, which includes a nitrophenyl group and an iodoacetate moiety. It typically appears as a yellow crystalline solid and is known for its reactivity, particularly in nucleophilic substitution reactions. The presence of the nitro group enhances the electrophilicity of the iodoacetate, making it a useful reagent in organic synthesis, particularly for the acylation of amines and alcohols. This compound is often utilized in biochemical applications, such as in the study of enzyme kinetics and protein labeling due to its ability to form stable covalent bonds with nucleophilic sites in biomolecules. p-Nitrophenyl iodoacetate is also sensitive to moisture and should be stored in a cool, dry place to maintain its stability. Safety precautions are necessary when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate personal protective equipment should be used.

Formula: C₈H₆INO₄

InChI: InChI=1S/C8H6INO4/c9-5-8(11)14-7-3-1-6(2-4-7)10(12)13/h1-4H,5H2

InChI key: InChIKey=GERXSZLDSOPHJV-UHFFFAOYSA-N

SMILES: O(C(CI)=O)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• 4-Nitrophenyl 2-iodoacetate
• Acetic acid, 2-iodo-, 4-nitrophenyl ester
• Acetic acid, iodo-, 4-nitrophenyl ester
• Acetic acid, iodo-, p-nitrophenyl ester
• p-Nitrophenyl iodoacetate
• NPIA
• 4-Nitrophenyl iodoacetate

4-Nitrophenyl Iodoacetate

CAS: 31252-85-4

4-Nitrophenyl Iodoacetate

Formula: C₈H₆INO₄

Purity: 99%

Molecular weight: 307.04

Ref: 54-OR1027494

4-Nitrophenyl iodoacetate

CAS: 31252-85-4

4-Nitrophenyl iodoacetate is a conjugate that contains an aldehyde group. It is highly reactive, and can be used to form conjugates with proteins, carbohydrates, nucleic acids, and other organic compounds. 4-Nitrophenyl iodoacetate reacts quickly with lysine residues in the presence of a base, forming an intermediate molecule that can react with various functional groups on the protein. This reaction occurs at a rate dependent on the concentration of substrate molecule and the pH of the solution. The product is then hydrolyzed to release 4-nitrophenol and acetate ions.

Formula: C₈H₆INO₄

Purity: Min. 95%

Molecular weight: 307.04 g/mol

Ref: 3D-FN06464

p-Nitrophenyl Iodoacetate

Controlled Product

CAS: 31252-85-4

Formula: C₈H₆INO₄

Color and Shape: Neat

Molecular weight: 307.04

Ref: TR-N503775

p-Nitrophenyl Iodoacetate

CAS: 31252-85-4

Formula: C₈H₆INO₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 307.0420

Ref: IN-DA003TTK