CAS 3125922-63-3

Formula: C29H23ClFN3O3

InChI: InChI=1S/C29H22FN3O3.ClH/c30-24-7-3-5-21(15-24)17-32-14-4-6-22(18-32)16-31-27(34)23-12-10-20(11-13-23)19-33-28(35)25-8-1-2-9-26(25)29(33)36;/h1-15,18H,16-17,19H2;1H

InChI key: JFPVFHXAPIFVGC-UHFFFAOYSA-N

SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)CC3=CC=C(C=C3)C(=O)NCC4=C[N+](=CC=C4)CC5=CC(=CC=C5)F.[Cl-]

BChE-IN-39

CAS: 3125922-63-3

BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC₅₀ of 0.08 μM, while showing an IC₅₀ of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.

Formula: C₂₉H₂₃ClFN₃O₃

Color and Shape: Solid

Molecular weight: 515.963

Ref: TM-T204121