CAS 312946-37-5

LDN-27219

Description:

LDN-27219, with the CAS number 312946-37-5, is a chemical compound that has garnered interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized as a small molecule inhibitor, specifically targeting certain biological pathways that may be involved in disease processes. The compound exhibits a specific mechanism of action, which may include modulation of protein interactions or enzymatic activities. LDN-27219 is often studied for its effects on cellular signaling and its potential role in treating conditions such as cancer or neurodegenerative diseases. Its physicochemical properties, such as solubility, stability, and bioavailability, are critical for its efficacy and safety profile. Additionally, the compound undergoes various pharmacokinetic evaluations to understand its absorption, distribution, metabolism, and excretion (ADME) characteristics. As research continues, LDN-27219 may contribute to the development of novel therapeutic strategies, although further studies are necessary to fully elucidate its biological effects and clinical potential.

Formula: C₂₀H₁₆N₄O₂S₂

InChI: InChI=1S/C20H16N4O2S2/c21-23-16(25)12-28-20-22-18-17(15(11-27-18)13-7-3-1-4-8-13)19(26)24(20)14-9-5-2-6-10-14/h1-11H,12,21H2,(H,23,25)

InChI key: WLBUICQBNZXIDJ-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)C2=CSC3=C2C(=O)N(C(=N3)SCC(=O)NN)C4=CC=CC=C4

Synonyms:

• (LDN 27219
• 2-({4-oxo-3,5-diphenyl-3H,4H-thieno[2,3-d]pyrimid in-2-yl}sulfanyl)acetohydrazide
• LDN-27219
• CS-1194
• Acetic acid, 2-[(3,4-dihydro-4-oxo-3,5-diphenylthieno[2,3-d]pyrimidin-2-yl)thio]-, hydrazide
• LDN-27219 >=98% (HPLC)
• 2-((4-oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide
• 184663
• 2-[(3,4-Dihydro-4-oxo-3,5-diphenylthieno[2,3-d]pyrimidin-2-yl)thio]-acetic acid hydrazide

LDN-27219

CAS: 312946-37-5

LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.

Formula: C₂₀H₁₆N₄O₂S₂

Purity: 99.01% - 99.38%

Color and Shape: Solid

Molecular weight: 408.497

Ref: TM-T11831

LDN-27219

CAS: 312946-37-5

LDN-27219

Formula: C₂₀H₁₆N₄O₂S₂

Purity: ≥98%

Molecular weight: 408.5

Ref: 54-BUP05484

LDN-27219

CAS: 312946-37-5

Formula: C₂₀H₁₆N₄O₂S₂

Purity: %

Molecular weight: 408.4966

Ref: IN-DA00C6G4

LDN-27219

CAS: 312946-37-5

2-((4-Oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide

Formula: C₂₀H₁₆N₄O₂S₂

Purity: 99+%

Molecular weight: 408.49

Ref: IN-DG630634