CAS 313-67-7
:Aristolochic acid
Description:
Aristolochic acid is a naturally occurring compound derived from plants in the Aristolochiaceae family. It is primarily known for its presence in various traditional herbal remedies. The compound is characterized by its distinctive chemical structure, which includes a bicyclic system with a nitrogen atom, contributing to its biological activity. Aristolochic acid exhibits nephrotoxic and carcinogenic properties, raising significant health concerns, particularly in relation to its association with kidney damage and urothelial cancers. Its mechanism of action involves the formation of DNA adducts, leading to mutagenic effects. Due to these adverse effects, many countries have restricted or banned the use of herbal products containing aristolochic acid. The compound is typically found in the form of a white to pale yellow crystalline powder and is soluble in organic solvents but poorly soluble in water. Given its toxicological profile, research continues to explore its effects and the implications for human health, emphasizing the need for caution in the use of herbal medicines containing this substance.
Formula:C17H11NO7
InChI:InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20)
InChI key:InChIKey=BBFQZRXNYIEMAW-UHFFFAOYSA-N
SMILES:N(=O)(=O)C=1C=2C(C=3C(C1)=C(OC)C=CC3)=C4C(=CC2C(O)=O)OCO4
Synonyms:- 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid
- 8-Methoxy-3,4-methylendioxxy-10-nitro-1-phenanthrencarbonsaeure
- 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid
- 8-Methoxy-6-Nitrophenanthro[3,4-D][1,3]Dioxole-5-Carboxylate
- 8-Methoxy-6-Nitrophenanthro[3,4-D][1,3]Dioxole-5-Carboxylic Acid
- 8-Methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid
- Aristolochia A
- Aristolochiazaeure
- Aristolochic acid
- Aristolochic acid 1
- Aristolochic acid A
- Aristolochin
- Aristolochine
- Brn 0345159
- Ccris 1544
- Nsc 11926
- Nsc 50413
- Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-
- Tardolyt
- Tr 1736
- Aristolochic acid I
- See more synonyms
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Found 18 products.
Aristolochic acid A
CAS:Formula:C17H11NO7Purity:≥ 98.0%Color and Shape:Light yellow to dark yellow powderMolecular weight:341.27Aristolochic Acid
CAS:Formula:C17H11NO7Purity:>95.0%(T)(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:341.28Aristolochic acid A
CAS:Aristolochic acid, a potent human carcinogen produced by Aristolochia plants, is associated with urothelial carcinoma of the upper urinary tract (UUC), exposure to aristolochic acid contributes significantly to the incidence of UUC in Taiwan and endemic (Balkan) nephropathy .Formula:C17H11NO7Purity:95%~99%Color and Shape:Yellow powderMolecular weight:341.275Aristolochic acid A
CAS:<p>Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.</p>Formula:C17H11NO7Purity:99.85% - 99.97%Color and Shape:Yellow PowderMolecular weight:341.27Aristolochic acid i
CAS:Carboxylic acid with additional oxygen functionsFormula:C17H11NO7Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:341.28Aristolochic Acid A
CAS:Controlled Product<p>Applications Aristolochic acids occur in Aristolochiaceae and in butterflies feeding on these plants. One of a group of fourteen known, substituted 1-phenanthrenecarboxylic acids.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Coutts, et al.: J. Pharm. Pharmacol., 11, 607 (1959), Kupchan, D., et al.: J. Med. Pharm. Chem., 5, 657 (1962), Mix, D.B., et al.: J. Nat. Prod., 45, 657 (1982), Mengs, U., et al.: Arch. Toxixol., 59, 328 (1987),<br></p>Formula:C17H11NO7Color and Shape:NeatMolecular weight:341.272Aristolochic acid - Mixture of I and II
CAS:<p>Used in herbal products for gout, arthritis and inflammation; mutagen</p>Formula:C17H11NO7Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:341.27 g/molAristolochic acid I
CAS:<p>Used in herbal products for gout, arthritis and inflammation; mutagen</p>Formula:C17H11NO7Purity:Min. 95%Molecular weight:341.27 g/mol
