CAS 313-67-7: Aristolochic acid
Description:Aristolochic acid is a naturally occurring compound derived from plants in the Aristolochiaceae family. It is primarily known for its presence in various traditional herbal remedies. The compound is characterized by its distinctive chemical structure, which includes a bicyclic system with a nitrogen atom, contributing to its biological activity. Aristolochic acid exhibits nephrotoxic and carcinogenic properties, raising significant health concerns, particularly in relation to its association with kidney damage and urothelial cancers. Its mechanism of action involves the formation of DNA adducts, leading to mutagenic effects. Due to these adverse effects, many countries have restricted or banned the use of herbal products containing aristolochic acid. The compound is typically found in the form of a white to pale yellow crystalline powder and is soluble in organic solvents but poorly soluble in water. Given its toxicological profile, research continues to explore its effects and the implications for human health, emphasizing the need for caution in the use of herbal medicines containing this substance.
Formula:C17H11NO7
InChI:InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20)
InChI key:InChIKey=BBFQZRXNYIEMAW-UHFFFAOYSA-N
SMILES:O=C(O)C1=CC=2OCOC2C3=C4C=CC=C(OC)C4=CC(=C13)N(=O)=O
- Synonyms:
- 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid
- 8-Methoxy-3,4-methylendioxxy-10-nitro-1-phenanthrencarbonsaeure
- 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid
- 8-Methoxy-6-Nitrophenanthro[3,4-D][1,3]Dioxole-5-Carboxylate
- 8-Methoxy-6-Nitrophenanthro[3,4-D][1,3]Dioxole-5-Carboxylic Acid
- 8-Methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid
- Aristolochia A
- Aristolochiazaeure
- Aristolochic acid
- Aristolochic acid 1
- See more synonyms
- Aristolochic acid A
- Aristolochin
- Aristolochine
- Brn 0345159
- Ccris 1544
- Nsc 11926
- Nsc 50413
- Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-
- Tardolyt
- Tr 1736
- Aristolochic acid I
- Aristolochic acid-I

Ref: 41-Y0001185
11mg | 115.00 € |

Ref: 41-Y0001323
140mg | 115.00 € |

Aristolochic acid I
Ref: IN-DA007JPY
1g | To inquire | ||
25mg | 114.00 € | ||
50mg | 152.00 € | ||
100mg | 162.00 € | ||
250mg | 258.00 € |

Ref: 54-BUP11187
25mg | 94.00 € | ||
50mg | 130.00 € | ||
100mg | 185.00 € | ||
500mg | 402.00 € |

Ref: 4Z-A-365006
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Ref: 54-OR1012300
1g | 743.00 € | ||
5g | 2,841.00 € | ||
100mg | 187.00 € | ||
250mg | 272.00 € |

Aristolochic acid A
Ref: 7W-GP8379
Undefined size | To inquire |

Aristolochic acid A
Ref: BP-BP0192
20mg | 81.00 € | ||
100mg | 166.00 € | ||
1000mg | 505.00 € |

Aristolochic acid I, 96%
Ref: AC-22609
100mg | To inquire | ||
500mg | To inquire |

Aristolochic Acid
Ref: 3B-A3599
100mg | 333.00 € |

Aristolochic acid A
Ref: TM-T2801
10mg | 47.00 € | ||
25mg | 60.00 € | ||
50mg | 88.00 € | ||
100mg | 113.00 € | ||
500mg | 265.00 € |

Ref: 4Z-A-365002
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Ref: 4Z-A-365001
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Aristolochic acid i
Ref: 5G-89565
10mg | 169.00 € | ||
50mg | 712.00 € | ||
250mg | 3,248.00 € | ||
500mg | 6,114.00 € | ||
1000mg | 11,464.00 € |

Aristolochic Acid A
Controlled ProductRef: TR-A771300
25mg | 145.00 € | ||
100mg | 441.00 € | ||
500mg | 1,611.00 € |

Aristolochic acid - Mixture of I and II
Ref: 3D-FA17982
1g | 1,480.00 € | ||
50mg | 318.00 € | ||
100mg | 447.00 € | ||
250mg | 663.00 € | ||
500mg | 1,005.00 € |

Aristolochic acid I
Ref: 3D-XA167153
1g | 1,480.00 € | ||
5g | 2,884.00 € | ||
100mg | 403.00 € | ||
500mg | 1,018.00 € |