CAS 314-03-4: Pimethixene

Description: Pimethixene is an anticholinergic medication primarily used for its antihistaminic properties. It is classified as a first-generation antihistamine and is known for its ability to block the action of histamine at H1 receptors, which helps alleviate allergic symptoms. The chemical structure of pimethixene includes a piperidine ring, contributing to its pharmacological activity. It is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. Pimethixene exhibits sedative effects, a common characteristic of first-generation antihistamines, due to its ability to cross the blood-brain barrier. Additionally, it may have antispasmodic properties, making it useful in treating conditions like motion sickness and certain gastrointestinal disorders. Side effects can include drowsiness, dry mouth, and blurred vision, which are typical of anticholinergic agents. As with any medication, it is important to use pimethixene under medical supervision to manage potential interactions and contraindications effectively.

Formula: C₁₉H₁₉NS

InChI: InChI=1S/C19H19NS/c1-20-12-10-14(11-13-20)19-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)19/h2-9H,10-13H2,1H3

InChI key: InChIKey=NZLVRVYNQYGMAB-UHFFFAOYSA-N

SMILES: S1C=2C=CC=CC2C(C=3C=CC=CC13)=C4CCN(C)CC4

Synonyms:

• 1-Methyl-4-(thioxanthen-9-ylidene)piperidine
• 1-Methyl-4-thioxanthen-9-ylidenepiperidine
• 1-methyl-4-(9H-thioxanthen-9-ylidene)piperidine
• 9-(1-Methyl-4-piperidinylidene)thioxanthene
• 9-(1-Methyl-4-piperidylidene)thioxanthene
• 9-(N-Methyl-4′-piperidylene)thioxanthene
• 9-(N-Methyl-4′-piperidylidene)-thioxanthene
• Bp 400
• Bp 400S
• Brn 4143937
• Calmixen
• Calmixene
• Cga 123427
• Mepithiathene
• Pimethixene [INN]
• Pimethixenum
• Pimethixenum [INN-Latin]
• Pimetixene
• Pimetixeno
• Pimetixeno [INN-Spanish]
• Piperidine, 1-methyl-4-(9H-thioxanthen-9-ylidene)-
• Piperidine, 1-methyl-4-(9H-thioxanthen-9-ylidene)- (9CI)
• Piperidine, 1-methyl-4-thioxanthen-9-ylidene-
• Unii-T46J20J26F
• Pimethixene

Pimethixene

CAS: 314-03-4

Pimethixene (Calmixen) blocks 5-HT1A, 2A/B/C, H1, D2/D4.4 & muscarinic M1/M2 receptors; potent with pKis 7.54-10.44.

• Formula: C₁₉H₁₉NS
• Purity: 97.50%
• Color and Shape: Solid
• Molecular weight: 293.43

Pimethixene

CAS: 314-03-4

• Purity: ≥98%
• Molecular weight: 293.43g/mol

Pimethixene

CAS: 314-03-4

• Formula: C₁₉H₁₉NS
• Color and Shape: Neat
• Molecular weight: 293.426

Pimethixene-d3

CAS: 314-03-4

Pimethixene-d3 is a potent anticancer drug that inhibits the transcriptional regulation of genes that are …

• Formula: C₁₉H₁₉NS
• Purity: Min. 95%
• Molecular weight: 293.4 g/mol