CAS 318-98-9

Propranolol hydrochloride

Description:

Propranolol hydrochloride is a non-selective beta-adrenergic antagonist, commonly used in the treatment of various cardiovascular conditions, including hypertension, angina, and arrhythmias, as well as for anxiety and migraine prophylaxis. It is a white to off-white crystalline powder that is soluble in water and alcohol, which facilitates its administration in oral and injectable forms. The chemical formula for propranolol hydrochloride is C16H21NO2·HCl, indicating the presence of a secondary amine and an aromatic ring, contributing to its pharmacological activity. The substance works by blocking the effects of epinephrine and norepinephrine on beta receptors, leading to decreased heart rate and blood pressure. Propranolol hydrochloride is typically administered in various dosages, depending on the condition being treated, and may have side effects such as fatigue, dizziness, and gastrointestinal disturbances. Its use requires careful monitoring, especially in patients with respiratory conditions or diabetes, due to potential contraindications and interactions with other medications.

Formula: C₁₆H₂₁NO₂·ClH

InChI: InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI key: InChIKey=ZMRUPTIKESYGQW-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C=1C2=C(C=CC1)C=CC=C2.Cl

Synonyms:

• (.+-.)-Propranolol hydrochloride
• (R,S)-Propranolol hydrochloride
• (RS)-Propranolol hydrochloride
• 1-(1-Naphthoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
• 1-(1-Naphthyloxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
• 1-(1-Naphthyloxy)-3-(isopropylamino)-2-propanol hydrochloride
• 1-(Isopropylamino)-3-(1-naphthoxy)-2-propanol hydrochloride
• 1-(Isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride
• 1-(Isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
• 1-(Naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol hydrochloride
• 1-Isopropylamino-3-naphthalen-1-yloxypropan-2-ol monohydrochloride
• 1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
• 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride
• 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride (1:1)
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Anapriline
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Propranolol hydrochloride
• Anaprilin
• Anapriline
• Angilol
• Apsolol
• Avlocardyl
• Bedranol
• Beprane
• Berkolol
• Beta-Neg
• Beta-Tablinen
• Beta-Timelets
• Betacap
• Cardinol
• Caridolol
• Chlorure De [2-Hydroxy-3-(Naphtyloxy)Propyl]Isopropylammonium
• Ciplar
• Cloruro De [2-Hidroxi-3-(Naftiloxi)Propil]Isopropilamonio
• DL-Anapriline
• Deralin
• Docitan
• Dociton
• Duranol
• Efektolol
• Elbol
• Frekven
• Hemangeol
• Hemangiol
• Ici 45520
• Inderal
• Inderal LA
• Inderalici
• Indobloc
• Intermigran
• Kemi S
• Monoprolol
• Naprilin
• Nsc 91523
• Obsidan
• Oposim
• Prano-Puren
• Prophylux
• Propranolol chloride
• Propranur
• Propraratiopharm
• Pylapron
• Rapynogen
• Sagittol
• Servanolol
• Sloprolol
• Sumial
• Tesnol
• [2-Hydroxy-3-(Naphthyloxy)Propyl]Isopropylammonium Chloride
• [2-Hydroxy-3-(naphthyloxy)propyl]isopropylammoniumchlorid
• dl-Propranolol hydrochloride

(+/-)-Propranolol hydrochloride, 99%

CAS: 318-98-9

A beta-adrenergic blocker This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the bran

Formula: C₁₆H₂₂ClNO₂

Purity: 99%

Color and Shape: White to pale cream, Powder or crystalline powder

Molecular weight: 295.81

Ref: 02-H26645

Propranolol Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 318-98-9

Color and Shape: Single Solution

Ref: 61-AMP0043.00-01

Propranolol Hydrochloride

CAS: 318-98-9

Color and Shape: Neat

Ref: 61-FOR0043.00

d,l-Propranolol.HCl

CAS: 318-98-9

Color and Shape: Neat

Ref: LP-PPN-1209-HC-10

d,l-Propranolol.HCl, 1mg/ml in Methanol (as free base)

CAS: 318-98-9

Color and Shape: Single Solution

Ref: LP-PPN-1209-HC-1LM

PROPRANOLOL FOR SYSTEM SUITABILITY CRS

CAS: 318-98-9

PROPRANOLOL FOR SYSTEM SUITABILITY CRS

Color and Shape: Powder

Ref: 41-Y0002135

PROPRANOLOL HYDROCHLORIDE CRS

CAS: 318-98-9

PROPRANOLOL HYDROCHLORIDE CRS

Formula: C₁₆H₂₃Cl₂NO₂

Color and Shape: Added

Molecular weight: 332.2653

Ref: 41-P3500000

PROPRANOLOL HYDROCHLORIDE RS

CAS: 318-98-9

PROPRANOLOL HYDROCHLORIDE RS

Formula: C₁₆H₂₃Cl₂NO₂

Color and Shape: Powder

Molecular weight: 332.2653

Ref: 41-ICRS0402

Propranolol hydrochloride

CAS: 318-98-9

Propranolol hydrochloride

Formula: C₁₆H₂₂ClNO₂

Purity: 99.5%

Color and Shape: Off White

Molecular weight: 295.13391

Ref: 47-1196

Propranolol Hydrochloride

CAS: 318-98-9

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₆H₂₁NO₂·HCl

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 295.13391

Ref: 45-1576005

[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine hydrochloride

CAS: 318-98-9

Formula: C₁₆H₂₂ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 295.8044

Ref: IN-DA003TZN

Propranolol HCl

CAS: 318-98-9

Formula: C₁₆H₂₁NO₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 259.35 36.46

Ref: 4Z-P-1610

Propranolol hydrochloride

CAS: 318-98-9

Formula: C₁₆H₂₁NO₂·HCl

Purity: 99.0 - 101.0 % (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 295.80

Ref: 7W-GP3553

Propranolol hydrochloride, BP grade

CAS: 318-98-9

Formula: C₁₆H₂₁NO₂·HCl

Purity: ≤ 0.1%

Color and Shape: White crystalline powder

Molecular weight: 295.80

Ref: 7W-GP5526

Propranolol hydrochloride

CAS: 318-98-9

Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse

Formula: C₁₆H₂₂ClNO₂

Purity: 99.94% - >99.99%

Color and Shape: White Or Almost White Powder White Powder

Molecular weight: 295.80

Ref: TM-T0812

Propranolol Hydrochloride

CAS: 318-98-9

Color and Shape: Neat

Ref: 86-MM0043.00

Propranolol hydrochloride

Controlled Product

CAS: 318-98-9

Formula: C₁₆H₂₁NO₂·ClH

Color and Shape: Neat

Molecular weight: 295.80

Ref: 04-C16501000

Propranolol Hydrochloride

CAS: 318-98-9, 525-66-6

Formula: C₁₆H₂₁NO₂·HCl

Purity: >99.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 295.81

Ref: 3B-P0995

N-Nitroso Pipamperone

CAS: 318-98-9

Formula: C₂₁H₂₉FN₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 404.49

Ref: 4Z-P-161004

rac-Propranolol Hydrochloride

Controlled Product

CAS: 318-98-9

Applications β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
References Bond, et al.: Nature, 213, 721 (1967), Hansteen, V., et al.: Br. Med. J., 284, 155 (1982), Diamond, S., et al.: J. Clin. Pharmacol., 28, 193 (1988),

Formula: C₁₆H₂₁NO₂·ClH

Color and Shape: Neat

Molecular weight: 295.80

Ref: TR-P831800

rac-Propranolol hydrochloride

Controlled Product

CAS: 318-98-9

Propranolol is a beta-adrenergic receptor antagonist that is used to treat high blood pressure, chest pain and heart failure. It also has been shown to be effective in the treatment of inflammatory bowel disease (IBD). Propranolol blocks the binding of proprotein convertase subtilisin/kexin type 9 (PCSK9) to its receptors, which inhibits the production of LDL cholesterol. In humans, propranolol is metabolized through hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The drug also has a synergic effect with other drugs such as erythromycin and phenobarbital. Propranolol binds to proteins in red blood cells and decreases diastolic pressure.

Formula: C₁₆H₂₂ClNO₂

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 295.8 g/mol

Ref: 3D-FP27655