CAS 318-98-9

Propranolol hydrochloride

Description:

Propranolol hydrochloride is a non-selective beta-adrenergic antagonist, commonly used in the treatment of various cardiovascular conditions, including hypertension, angina, and arrhythmias, as well as for anxiety and migraine prophylaxis. It is a white to off-white crystalline powder that is soluble in water and alcohol, which facilitates its administration in oral and injectable forms. The chemical formula for propranolol hydrochloride is C16H21NO2·HCl, indicating the presence of a secondary amine and an aromatic ring, contributing to its pharmacological activity. The substance works by blocking the effects of epinephrine and norepinephrine on beta receptors, leading to decreased heart rate and blood pressure. Propranolol hydrochloride is typically administered in various dosages, depending on the condition being treated, and may have side effects such as fatigue, dizziness, and gastrointestinal disturbances. Its use requires careful monitoring, especially in patients with respiratory conditions or diabetes, due to potential contraindications and interactions with other medications.

Formula: C₁₆H₂₁NO₂·ClH

InChI: InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI key: InChIKey=ZMRUPTIKESYGQW-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C=1C2=C(C=CC1)C=CC=C2.Cl

Synonyms:

• (.+-.)-Propranolol hydrochloride
• (R,S)-Propranolol hydrochloride
• (RS)-Propranolol hydrochloride
• 1-(1-Naphthoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
• 1-(1-Naphthyloxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
• 1-(1-Naphthyloxy)-3-(isopropylamino)-2-propanol hydrochloride
• 1-(Isopropylamino)-3-(1-naphthoxy)-2-propanol hydrochloride
• 1-(Isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride
• 1-(Isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
• 1-(Naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol hydrochloride
• 1-Isopropylamino-3-naphthalen-1-yloxypropan-2-ol monohydrochloride
• 1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
• 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride
• 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride (1:1)
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Anapriline
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Propranolol hydrochloride
• Anaprilin
• Anapriline
• Angilol
• Apsolol
• Avlocardyl
• Bedranol
• Beprane
• Berkolol
• Beta-Neg
• Beta-Tablinen
• Beta-Timelets
• Betacap
• Cardinol
• Caridolol
• Chlorure De [2-Hydroxy-3-(Naphtyloxy)Propyl]Isopropylammonium
• Ciplar
• Cloruro De [2-Hidroxi-3-(Naftiloxi)Propil]Isopropilamonio
• DL-Anapriline
• Deralin
• Docitan
• Dociton
• Duranol
• Efektolol
• Elbol
• Frekven
• Hemangeol
• Hemangiol
• Ici 45520
• Inderal
• Inderal LA
• Inderalici
• Indobloc
• Intermigran
• Kemi S
• Monoprolol
• Naprilin
• Nsc 91523
• Obsidan
• Oposim
• Prano-Puren
• Prophylux
• Propranolol chloride
• Propranur
• Propraratiopharm
• Pylapron
• Rapynogen
• Sagittol
• Servanolol
• Sloprolol
• Sumial
• Tesnol
• [2-Hydroxy-3-(Naphthyloxy)Propyl]Isopropylammonium Chloride
• [2-Hydroxy-3-(naphthyloxy)propyl]isopropylammoniumchlorid
• dl-Propranolol hydrochloride

rac-Propranolol hydrochloride

Controlled Product

CAS: 318-98-9

Propranolol is a beta-adrenergic receptor antagonist that is used to treat high blood pressure, chest pain and heart failure. It also has been shown to be effective in the treatment of inflammatory bowel disease (IBD). Propranolol blocks the binding of proprotein convertase subtilisin/kexin type 9 (PCSK9) to its receptors, which inhibits the production of LDL cholesterol. In humans, propranolol is metabolized through hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The drug also has a synergic effect with other drugs such as erythromycin and phenobarbital. Propranolol binds to proteins in red blood cells and decreases diastolic pressure.

Formula: C₁₆H₂₂ClNO₂

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 295.8 g/mol

Ref: 3D-FP27655