CAS: 319460-85-0 - Axitinib

Formula: C₂₂H₁₈N₄OS

InChI: InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+

InChI key: InChIKey=RITAVMQDGBJQJZ-FMIVXFBMSA-N

SMILES: O=C(NC)C=1C=CC=CC1SC=2C=CC=3C(=NNC3C2)C=CC4=NC=CC=C4

Synonyms:

• Ag 013736
• Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-
• Inlyta
• N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide
• N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
• N-methyl-2-({3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl}sulfanyl)benzamide

(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide

CAS: 319460-85-0

• Formula: C₂₂H₁₈N₄OS
• Color and Shape: Solid
• Molecular weight: 386.4695

Axitinib

CAS: 319460-85-0

Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, …

• Formula: C₂₂H₁₈N₄OS
• Purity: 99.81%
• Color and Shape: Off-White Solid
• Molecular weight: 386.47

Axitinib

CAS: 319460-85-0

• Formula: C₂₂H₁₈N₄OS
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 386.47

Axitinib

CAS: 319460-85-0

• Formula: C₂₂H₁₈N₄OS
• Color and Shape: Off-White Solid
• Molecular weight: 386.47

Axitinib

CAS: 319460-85-0

• Formula: C₂₂H₁₈N₄OS
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 386.47

Axitinib

CAS: 319460-85-0

• Formula: C₂₂H₁₈N₄OS
• Color and Shape: Neat
• Molecular weight: 386.47

Axitinib

CAS: 319460-85-0

• Formula: C₂₂H₁₈N₄OS
• Color and Shape: Off White Solid
• Molecular weight: 386.47

Axitinib

CAS: 319460-85-0

Inhibits VEGFR1, VEGFR2, VEGFR3, c-kit and PDGFR tyrosine kinases

• Formula: C₂₂H₁₈N₄OS
• Purity: Min. 98 Area-%
• Color and Shape: White Yellow Powder
• Molecular weight: 386.47 g/mol

N-methyl-2-[[3-[(1E)-2-(pyridinyl) ethenyl]-[N-[(5hydroxy methyl furanyl)-hydroxymethyl]-1H-indazol-6-yl-thiol]]-benzamide

CAS: 319460-85-0

• Formula: C₂₈H₂₄N₄O₄S
• Molecular weight: 512.58