CAS 3247-10-7
:Vincadifformine
Description:
Vincadifformine, with the CAS number 3247-10-7, is a chemical compound that belongs to the class of alkaloids derived from the periwinkle plant, specifically from the genus Catharanthus. It is known for its structural similarity to other vinca alkaloids, which are recognized for their biological activity, particularly in the field of pharmacology. Vincadifformine exhibits properties that may influence various physiological processes, making it of interest in medicinal chemistry. The compound typically presents as a white to off-white solid and is soluble in organic solvents. Its potential applications include research into its effects on cell division and cancer treatment, as vinca alkaloids are often used in chemotherapy regimens. However, detailed studies on its specific pharmacological effects, toxicity, and therapeutic potential are necessary to fully understand its utility in clinical settings. As with many alkaloids, safety and handling precautions are essential due to their bioactive nature.
Formula:C21H26N2O2
InChI:InChI=1/C21H26N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-5,7-8,19,22H,3,6,9-13H2,1-2H3/t19-,20-,21-/m0/s1
InChI key:InChIKey=GIGFIWJRTMBSRP-ACRUOGEOSA-N
SMILES:C(C)[C@@]12[C@]3([C@@]4(C(=C(C(OC)=O)C1)NC=5C4=CC=CC5)CCN3CCC2)[H]
Synonyms:- 15-Bromovincadifformine
- 1H-Indolizino[8,1-cd]carbazole, aspidospermidine-3-carboxylic acid deriv.
- Aspidospermidine-3-carboxylic acid, 2,3-didehydro-, methyl ester, (5α,12β,19α)-
- 6,7-Dihydrotabersonine
- Aspidospermidine-3-carboxylic acid, 2,3-didehydro-, methyl ester, (5alpha,12beta,19alpha)-
- Tabersonine, 6,7-dihydro-
- methyl (5alpha,12beta,19alpha)-2,3-didehydroaspidospermidine-3-carboxylate
- Aspidospermidine-3-carboxylic acid, 2,3-didehydro-, methyl ester, (5α,12R,19α)-
- Vincadifformine
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(-)-Vincadifformine
CAS:Controlled ProductFormula:C21H26N2O2Color and Shape:NeatMolecular weight:338.443(-)-Vincadifformine-D4
CAS:Controlled ProductApplications (-)-Vincadifformine-D4 is an intermediate used in the synthesis of Apovincaminic Acid-d4 (A729252), which is the main labelled metabolite of Vinpocetine (V332502), a vasodilator cerebral.
References Miskolczi, P., et al.: Eur. J. Clin. Pharmacol., 33, 185 (1987), Kiss, B., et al.: Eur. J. Pharmacol., 209, 109 (1991), Stephenson, D., et al.: J. Neurosci., 15, 5263 (1995),Formula:C21D4H22N2O2Color and Shape:NeatMolecular weight:342.468

