CAS 325855-74-1

2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-, 1'-oxide

Description:

2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-, 1'-oxide, identified by CAS number 325855-74-1, is a chemical compound that features a bipyridine core structure, which consists of two pyridine rings connected by a carbon-carbon bond. This compound is characterized by the presence of a chlorine atom at the 5-position and a methyl group at the 6-position of one pyridine ring, while the other ring is substituted with a 4-(methylsulfonyl)phenyl group at the 3-position. The presence of the methylsulfonyl group enhances its solubility and may influence its reactivity and biological activity. The 1'-oxide designation indicates that there is an oxidation at the nitrogen atom of the bipyridine structure, which can affect the compound's electronic properties and potential interactions with biological targets. Overall, this compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development.

Formula: C₁₈H₁₅ClN₂O₃S

InChI: InChI=1S/C18H15ClN2O3S/c1-12-3-4-14(11-21(12)22)18-17(9-15(19)10-20-18)13-5-7-16(8-6-13)25(2,23)24/h3-11H,1-2H3

InChI key: KMLFAHIIJSUUPX-UHFFFAOYSA-N

SMILES: CC1=[N+](C=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C)[O-]

Etoricoxib N-Oxide

CAS: 325855-74-1

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₈H₁₅ClN₂O₃S

Color and Shape: Off-White Solid

Molecular weight: 374.04919

Ref: 45-1A19170

Etoricoxib N1'-oxide

CAS: 325855-74-1

Etoricoxib N1'-oxide

Purity: 98%

Molecular weight: 374.84g/mol

Ref: 54-OR1034249

Etoricoxib N-Oxide 1

CAS: 325855-74-1

Formula: C₁₈H₁₅ClN₂O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 374.84

Ref: 4Z-E-454

5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1'-oxide

CAS: 325855-74-1

Formula: C₁₈H₁₅ClN₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 374.8413

Ref: IN-DA00C93X

Etoricoxib N1'-oxide

Controlled Product

CAS: 325855-74-1

Formula: C₁₈H₁₅ClN₂O₃S

Color and Shape: Neat

Molecular weight: 374.84

Ref: 04-C13365100

Etoricoxib N1’-Oxide

CAS: 325855-74-1

Formula: C₁₈H₁₅ClN₂O₃S

Molecular weight: 374.8

Ref: ST-EA-CP-E1031

5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1'-oxide

CAS: 325855-74-1

Purity: 98%

Molecular weight: 374.8399963

Ref: 10-F054417

Etoricoxib N1’-Oxide

Controlled Product

CAS: 325855-74-1

Applications Etoricoxib N1’-Oxide is an impurity of Etoricoxib (E934100).
References Friesen, R., et al.: Bioorg. Med. Lett., 8, 2777 (1998), Botting, J., et al.: Drugs of Today, 35, 225 (19990, Talley, J., et al.: J. Med. Chem., 43, 775 (2000),

Formula: C₁₈H₁₅ClN₂O₃S

Color and Shape: Neat

Molecular weight: 374.84

Ref: TR-E934115

Etoricoxib N-Oxide

CAS: 325855-74-1

Etoricoxib N-Oxide is a non-steroidal anti-inflammatory drug (NSAID) that is used to treat inflammation and pain. Etoricoxib N-Oxide has a short half-life, which is due to its rapid metabolism by CYP2C9 and CYP3A4. This drug has been shown to be effective in reducing the incidence of ulcers in horses treated with it orally for 3 months. Etoricoxib N-Oxide also inhibits the production of prostaglandins, which are substances that cause pain and inflammation. NSAIDs like etoricoxib N-Oxide inhibit the activity of cyclooxygenase (COX), an enzyme that converts arachidonic acid into prostaglandins. The inhibition of COX prevents the formation of prostaglandin H2 from arachidonic acid, which is a precursor to other prostaglandins such as PGE2 and PGD2. Et

Formula: C₁₈H₁₅ClN₂O₃S

Purity: Min. 95%

Molecular weight: 374.8 g/mol

Ref: 3D-FE179779

Etoricoxib N1'-oxide

CAS: 325855-74-1

EtoricoxibN1'-oxide is a metabolite of Etoricoxib. It does not inhibit COX-1 and does not significantly inhibit COX-2.

Formula: C₁₈H₁₅ClN₂O₃S

Color and Shape: Solid

Molecular weight: 374.841

Ref: TM-TYD-02100