CAS 328-50-7

2-Oxoglutaric acid

Description:

2-Oxoglutaric acid, also known as alpha-ketoglutarate, is a key intermediate in the Krebs cycle, which is essential for cellular respiration and energy production in aerobic organisms. It is a dicarboxylic acid with the molecular formula C5H6O5 and features two carboxyl groups (-COOH) and a ketone group (C=O). This compound is typically found in its anionic form, known as alpha-ketoglutarate, at physiological pH. It plays a crucial role in amino acid metabolism and the synthesis of neurotransmitters. Additionally, 2-oxoglutaric acid is involved in the regulation of cellular processes, including the modulation of gene expression and the maintenance of cellular redox balance. It is also studied for its potential therapeutic applications, including its role as a dietary supplement for enhancing athletic performance and its involvement in various metabolic disorders. The compound is generally recognized as safe when used appropriately, but its effects can vary based on dosage and individual health conditions.

Formula: C₅H₆O₅

InChI: InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

InChI key: InChIKey=KPGXRSRHYNQIFN-UHFFFAOYSA-N

SMILES: C(CCC(O)=O)(C(O)=O)=O

Synonyms:

• 2-Ketoglutaric acid
• 2-Oxo-1,5-pentanedioic acid
• 2-Oxoglutaric Acid
• 2-Oxoglutarsaure
• 2-Oxopentanedioic acid
• Acide 2-oxoglutarique
• Acido 2-Oxoglutarico
• Glutaric acid, 2-oxo-
• Nsc 17391
• α-Ketoglutaric acid
• α-Oxoglutaric acid
• α-Oxopentanedioic acid
• α-keto-Glutaric acid
• 2-oxo-pentanedioicaci
• alpha-Ketoglutaric Acid
• 2-Oxpentanedioicacid
• 2-oxopentanedioate
• 2-KETOGLUTARIC ACID, DISODIUM SALT, DIHYDRATE BIOTECh GRADE 99.5%
• diammonium 2-oxopentanedioate
• 2-KETOGLUTARIC ACID 99+%
• Oxoglutaric acid
• KETO-GLU
• GAMMA-KETOGLUTARIC ACID
• -Ketoglutaricacid
• α-Ketoglutaricacid
• A-KETOGLUTARIC ACID FREE ACID CELL*CULTU RE TESTED
• 2-OXOPENTANDIOICACID
• Glutaric acid, alpha keto
• KetoglutaricAcid,FreeAcid
• N-oxoglutamic acid
• 2-KETOGLUTARIC ACID BIOSYNTH
• alpha-keto-Glutaric acid
• Pentanedioic acid, 2-oxo-
• A-KetoglutaricAcidPuriss
• FEMA 3891
• 2-Oxo-1,5-dipentanedioic acid
• PENTANEDIOIC ACID, 2-OXO-

2-Oxoglutaric Acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purity: >99.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 146.10

Ref: 3B-K0005

2-Ketoglutaric acid, 98%

CAS: 328-50-7

2-Ketoglutaric acid is used as an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. It is also used in dietary supplements to improve protein synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. So

Formula: C₅H₆O₅

Purity: 98%

Color and Shape: White to pale yellow, Crystals or powder or crystalline powder

Molecular weight: 146.10

Ref: 02-A10256

2-Ketoglutaric Acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 146.0981

Ref: IN-DA003HHY

2-Ketoglutaric acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purity: (Titration) 98.0 - 101.5 %

Color and Shape: White to off-white crystalline powder

Molecular weight: 146.10

Ref: 7W-GP9006

2-Ketoglutaric acid

CAS: 328-50-7

2-Ketoglutaric acid

Purity: ≥98%

Molecular weight: 146.1g/mol

Ref: 54-BUP19492

2-Oxopentanedioic acid

CAS: 328-50-7

2-Oxopentanedioic acid

Formula: C₅H₆O₅

Purity: 95

Color and Shape: white to off white solid

Molecular weight: 146.10g/mol

Ref: 54-OR4662

2-Oxo-1,5-pentanedioic Acid-d6

CAS: 1173021-86-7, 328-50-7

Purity: 98 atom % D

Molecular weight: 152.14

Ref: 3U-D8105

2-Ketoglutaric acid

CAS: 328-50-7

2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle. High-Quality, Low-Cost!

Formula: C₅H₆O₅

Purity: 99.28%

Color and Shape: Solid

Molecular weight: 146.1

Ref: TM-T5980

2-Oxopentanedioic acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purity: 95%

Color and Shape: Powder or Crystalline Powder

Molecular weight: 146.098

Ref: 10-F069250

2-Ketoglutaric Acid

CAS: 328-50-7

Applications 2-Ketoglutaric Acid is a derivative of glutaric acid and is an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate.
References Son, J.Y., et al.: Nature., 496, 7443 (2013); Quartarao, C.E., et al.: Biochem., 52, 1765 (2013); Yum, S.H., et al.: Euro.J. Pharmacol., 699, 124 (2013);

Formula: C₅H₆O₅

Color and Shape: Off White Powder

Molecular weight: 146.10

Ref: TR-K191200

2-Ketoglutaric acid

CAS: 328-50-7

Used to differentiate microorganisms based on their metabolic properties.

Formula: C₅H₆O₅

Molecular weight: 146.10 g/mol

Ref: 3D-K-2400

a-Ketoglutaric acid

CAS: 328-50-7

a-Ketoglutaric acid is a naturally occurring organic compound that is found in the body as well as in plants. It belongs to the group of organic acids and is produced from the breakdown of amino acids, such as leucine and valine. a-Ketoglutaric acid has been shown to have physiological effects on cells and tissues by inhibiting enzymes involved in energy metabolism. In vitro assays have shown that a-ketoglutaric acid has inhibitory properties against plant metabolism. This drug also inhibits the transcriptional regulation of genes for fatty acid synthesis in human erythrocytes.
A-ketoglutaric acid has also been shown to inhibit glucose production in rat liver cells, which may be due to its ability to bind covalently with proteins or lipids, changing their structures and functions.

Formula: C₅H₆O₅

Color and Shape: White Off-White Powder

Molecular weight: 146.1 g/mol

Ref: 3D-FK09820

a-Ketoglutaric Acid (High Purity) extrapure AR, 99.5%

CAS: 328-50-7

Formula: C₅H₆O₅

Purity: min. 99.5%

Color and Shape: White to pale yellow, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 146.10

Ref: SR-28386

a-Ketoglutaric Acid extrapure, 99%

CAS: 328-50-7

Formula: C₅H₆O₅

Purity: min. 99%

Color and Shape: White to pale yellow, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 146.10

Ref: SR-93929