CAS 32860-56-3: 6-O-Tosyl-α-cyclodextrin

Description: 6-O-Tosyl-α-cyclodextrin is a modified derivative of α-cyclodextrin, which is a cyclic oligosaccharide composed of six glucose units. The modification involves the introduction of a tosyl group at the 6-position of the glucose unit, enhancing its solubility and reactivity. This compound typically exhibits characteristics such as increased lipophilicity compared to unmodified α-cyclodextrin, allowing it to form inclusion complexes with various hydrophobic guest molecules. It is often utilized in pharmaceutical applications for drug delivery and formulation, as it can improve the solubility and stability of poorly soluble drugs. Additionally, 6-O-tosyl-α-cyclodextrin can serve as a chiral selector in chromatography and as a reagent in organic synthesis. Its ability to form host-guest complexes makes it valuable in various fields, including materials science and biochemistry. Safety and handling precautions should be observed, as with any chemical substance, to mitigate potential hazards associated with its use.

Formula: C₄₃H₆₆O₃₂S

InChI: InChI=1S/C43H66O32S/c1-12-2-4-13(5-3-12)76(61,62)63-11-19-37-25(54)31(60)43(69-19)74-36-18(10-48)67-41(29(58)23(36)52)72-34-16(8-46)65-39(27(56)21(34)50)70-32-14(6-44)64-38(26(55)20(32)49)71-33-15(7-45)66-40(28(57)22(33)51)73-35-17(9-47)68-42(75-37)30(59)24(35)53/h2-5,14-60H,6-11H2,1H3/t14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-/m1/s1

InChI key: InChIKey=ARQITQMHQNGIEE-FUPLYMQKSA-N

SMILES: O=S(=O)(OCC1OC2OC3C(O)C(O)C(OC3CO)OC4C(O)C(O)C(OC4CO)OC5C(O)C(O)C(OC5CO)OC6C(O)C(O)C(OC6CO)OC7C(O)C(O)C(OC7CO)OC1C(O)C2O)C8=CC=C(C=C8)C

Synonyms:

• α-Cyclodextrin, 6A-(4-methylbenzenesulfonate)
• 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane, α-cyclodextrin deriv.
• α-Cyclodextrin, 6-p-toluenesulfonate
• Mono-6-O-p-toluenesulfonyl-α-cyclodextrin
• 6-O-Tosyl-α-cyclodextrin

Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin

CAS: 32860-56-3

• Formula: C₄₃H₆₆O₃₂S
• Purity: >85.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 1,127.03

MONO-6-O-(P-TOLUENESULFONYL)-α-CYCLODEXTRIN

CAS: 32860-56-3

• Formula: C₄₃H₆₆O₃₂S
• Purity: 85.0%
• Color and Shape: Solid
• Molecular weight: 1127.0299

Mono-6-O-(p-toluenesulfonyl)-a-cyclodextrin

CAS: 32860-56-3

Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) …

• Formula: C₄₃H₆₆O₃₂S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 1,127.03 g/mol