CAS 32860-56-3

6-O-Tosyl-α-cyclodextrin

Description:

6-O-Tosyl-α-cyclodextrin is a modified derivative of α-cyclodextrin, which is a cyclic oligosaccharide composed of six glucose units. The modification involves the introduction of a tosyl group at the 6-position of the glucose unit, enhancing its solubility and reactivity. This compound typically exhibits characteristics such as increased lipophilicity compared to unmodified α-cyclodextrin, allowing it to form inclusion complexes with various hydrophobic guest molecules. It is often utilized in pharmaceutical applications for drug delivery and formulation, as it can improve the solubility and stability of poorly soluble drugs. Additionally, 6-O-tosyl-α-cyclodextrin can serve as a chiral selector in chromatography and as a reagent in organic synthesis. Its ability to form host-guest complexes makes it valuable in various fields, including materials science and biochemistry. Safety and handling precautions should be observed, as with any chemical substance, to mitigate potential hazards associated with its use.

Formula: C₄₃H₆₆O₃₂S

InChI: InChI=1S/C43H66O32S/c1-12-2-4-13(5-3-12)76(61,62)63-11-19-37-25(54)31(60)43(69-19)74-36-18(10-48)67-41(29(58)23(36)52)72-34-16(8-46)65-39(27(56)21(34)50)70-32-14(6-44)64-38(26(55)20(32)49)71-33-15(7-45)66-40(28(57)22(33)51)73-35-17(9-47)68-42(75-37)30(59)24(35)53/h2-5,14-60H,6-11H2,1H3/t14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-/m1/s1

InChI key: InChIKey=ARQITQMHQNGIEE-FUPLYMQKSA-N

SMILES: C(OS(=O)(=O)C1=CC=C(C)C=C1)[C@@H]2[C@]3(O[C@]4(O[C@H](CO)[C@]([C@H](O)[C@H]4O)(O[C@]5(O[C@H](CO)[C@]([C@H](O)[C@H]5O)(O[C@]6(O[C@H](CO)[C@@](O[C@]7(O[C@H](CO)[C@@](O[C@]8(O[C@H](CO)[C@@](O[C@@](O2)([C@H](O)[C@H]3O)[H])([C@H](O)[C@H]8O)[H])[H])([C@H](O)[C@H]7O)[H])[H])([C@H](O)[C@H]6O)[H])[H])[H])[H])[H])[H])[H]

Synonyms:

• α-Cyclodextrin, 6A-(4-methylbenzenesulfonate)
• 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane, α-cyclodextrin deriv.
• α-Cyclodextrin, 6-p-toluenesulfonate
• Mono-6-O-p-toluenesulfonyl-α-cyclodextrin
• 6-O-Tosyl-α-cyclodextrin

Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin

CAS: 32860-56-3

Formula: C₄₃H₆₆O₃₂S

Purity: >85.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 1,127.03

Ref: 3B-M1644

Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin

CAS: 32860-56-3

Formula: C₄₃H₆₆O₃₂S

Purity: 85.0%

Color and Shape: Solid

Molecular weight: 1127.0299

Ref: IN-DA003S5B

Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin

CAS: 32860-56-3

Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin

Purity: >85.0%

Ref: 54-OR1079061

Mono-6-O-(p-toluenesulfonyl)-a-cyclodextrin

CAS: 32860-56-3

Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.

Formula: C₄₃H₆₆O₃₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 1,127.03 g/mol

Ref: 3D-OM11971