CAS 328933-56-8

Formula: C36H42N2O9

InChI: InChI=1S/C36H42N2O9/c1-22-28-20-27(46-36-33(42)31(40)32(41)34(47-36)35(43)44)14-15-29(28)38(30(22)24-8-10-25(39)11-9-24)21-23-6-12-26(13-7-23)45-19-18-37-16-4-2-3-5-17-37/h6-15,20,31-34,36,39-42H,2-5,16-19,21H2,1H3,(H,43,44)/t31-,32-,33+,34-,36+/m0/s1

InChI key: PAAXRVKIJQNQMY-VNOFEJHXSA-N

SMILES: CC1=C(N(C2=C1C=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)CC4=CC=C(C=C4)OCCN5CCCCCC5)C6=CC=C(C=C6)O

Bazedoxifene-5-Glucuronide

CAS: 328933-56-8

Formula: C₃₆H₄₂N₂O₉

Color and Shape: Off-White Solid

Molecular weight: 646.74

Ref: 4Z-B-484

Bazedoxifene-5-Glucuronide-d4

CAS: 328933-56-8

Formula: C₃₆H₃₈N₂O₉D₄

Color and Shape: White To Off-White Solid

Molecular weight: 650.77

Ref: 4Z-B-488

Bazedoxifene 5-β-D-Glucuronide Sodium

Controlled Product

CAS: 328933-56-8

Formula: C₃₆H₄₁N₂O₉·Na

Color and Shape: Neat

Molecular weight: 646.727

Ref: TR-B129275

Bazedoxifene-d4 5-β-D-Glucuronide

Controlled Product

CAS: 328933-56-8

Formula: C₃₆H₃₈D₄N₂O₉

Color and Shape: Neat

Molecular weight: 650.76

Ref: TR-B129277

Bazedoxifene 5-β-D-glucuronide

CAS: 328933-56-8

Bazedoxifene 5-β-D-glucuronide is an analog of bazedoxifene, a selective estrogen receptor modulator used in the treatment of osteoporosis. This compound has shown promising anticancer properties and has been studied extensively in Chinese hamster ovary cells. Bazedoxifene 5-β-D-glucuronide has been found to induce apoptosis in cancer cells and inhibit the activity of kinases involved in tumor growth. It is a potent inhibitor of several human protein kinases, including cyclin-dependent kinase 2 (CDK2) and glycogen synthase kinase 3 beta (GSK3β), which are important targets for medicinal chemists developing kinase inhibitors. This compound is excreted primarily in urine and may have potential as a therapeutic agent for various types of cancer.

Formula: C₃₆H₄₂N₂O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 646.7 g/mol

Ref: 3D-DNA93356

Bazedoxifene-5-Glucuronide

CAS: 328933-56-8

Formula: C₃₆H₄₂N₂O₉

Molecular weight: 646.74

Ref: ST-EA-CP-B41011