CAS 329-98-6

Phenylmethylsulfonyl fluoride

Description:

Phenylmethylsulfonyl fluoride (PMSF) is an organic compound characterized by its sulfonyl fluoride functional group, which contributes to its reactivity. It is typically a white to off-white crystalline solid at room temperature and is soluble in organic solvents such as acetone and ethanol, but has limited solubility in water. PMSF is primarily used as a serine protease inhibitor in biochemical research, making it valuable in the study of enzyme kinetics and protein purification. Its mechanism of action involves the formation of a covalent bond with the active site serine residue of enzymes, thereby inhibiting their activity. Additionally, PMSF is sensitive to moisture and should be stored in a dry environment to maintain its stability. Safety precautions are necessary when handling this compound, as it can be irritating to the skin, eyes, and respiratory system. Overall, PMSF is an important reagent in molecular biology and biochemistry, particularly in studies involving proteolytic enzymes.

Formula: C₇H₇FO₂S

InChI: InChI=1/C7H7FO2S/c1-6-4-2-3-5-7(6)11(8,9)10/h2-5H,1H3

InChI key: InChIKey=YBYRMVIVWMBXKQ-UHFFFAOYSA-N

SMILES: C(S(F)(=O)=O)C1=CC=CC=C1

Synonyms:

• .alpha.-Toluenesulfonyl fluoride
• Benzenemethanesulfonyl Fluoride
• Fluorure de phénylméthanesulfonyle
• Phenylmethanesulfonyl fluoride
• Phenylmethansulfonylfluorid
• 2-Methylbenzenesulfonyl Fluoride
• Pmsf
• Phenylmethylsulfonyl fluoride
• Benzylsulfonyl fluoride
• Fluorure d'α-toluenesulfonyle
• Fluoruro De Α-Toluenosulfonilo
• Nsc 88499
• α-Toluenesulfonyl fluoride
• α-Toluolsulfonylfluorid
• PHENYLMETHYLSUFONYL FLUORIDE
• A-TOLUENESULPHONYL FLUORIDE
• 4-TOLUENESULPHONYL FLUORIDE
• P-TOLUENESULPHONYL FLUORIDE
• PHENYLMETHANESULPHONYL FLUORIDE
• 4-TOLUENESULFONYL FLUORIDE
• PMSF PLUS
• PHENYLMETHYLSULPHONYL FLUORIDE
• PHENYLMETHANESULFONIC ACID FLUORIDE
• ALPHA-TOLUENESULPHONYL FLUORIDE
• PHENYLMETHANSULFOFLUORIDE
• P-TOLUENESULFONYL FLUORIDE

Benzylsulfonyl Fluoride [for Biochemical Research]

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 174.19

Ref: 3B-B3473

Benzylsulfonyl Fluoride

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 174.19

Ref: 3B-B1062

α-Toluenesulfonyl fluoride, 99%

CAS: 329-98-6

-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity. This Thermo Scientific Chemicals brand product

Formula: C₇H₇FO₂S

Purity: 99%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 174.19

Ref: 02-B22146

Phenylmethylsulfonyl fluoride

CAS: 329-98-6

PMSF inhibits serine proteases such as trypsin and chymotrypsin, cysteine proteases such as papain, and acetylcholinesterase.

Formula: C₇H₇FO₂S

Color and Shape: White

Molecular weight: 174.2

Ref: 01-4000472

Benzenemethanesulfonyl fluoride

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: 99%

Color and Shape: Solid

Molecular weight: 174.1927

Ref: IN-DA00I6AP

PMSF

CAS: 329-98-6

PMSF (Phenylmethylsulfonyl fluoride) is an irreversible inhibitor of serine/cysteine protease , preparation of cell lysates. High-Quality, Low-Cost!

Formula: C₇H₇FO₂S

Purity: 97.75% - 99.88%

Color and Shape: White To Cream Solid

Molecular weight: 174.19

Ref: TM-T0789

Phenylmethanesulfonyl fluoride

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: (Titration) ≥ 98.0%

Color and Shape: White to almost white crystalline powder or crystals

Molecular weight: 174.19

Ref: 7W-GE4342

PMSF

CAS: 329-98-6

PMSF

Purity: ≥95%

Molecular weight: 174.19g/mol

Ref: 54-BUP14950

Phenylmethanesulphonyl fluoride

CAS: 329-98-6

Phenylmethanesulphonyl fluoride

Formula: C₇H₇FO₂S

Purity: 99%

Color and Shape: white crystalline solid

Molecular weight: 174.19268g/mol

Ref: 54-PC6222M

Phenylmethanesulphonyl fluoride

CAS: 329-98-6

Phenylmethanesulphonyl fluoride

Formula: C₇H₇FO₂S

Purity: 99%

Color and Shape: white crystalline powder

Molecular weight: 174.19g/mol

Ref: 54-BIP0329

Phenylmethylsulfonyl Fluoride

Controlled Product

CAS: 329-98-6

Stability Moisture Sensitive
Applications Phenylmethylsulfonyl Fluoride Is a Phospholipase C inhibitor that ameliorates post-ischemic neuronal damage, nonspecific irreversible inhibitor of serine protease and other enzymes, including trypsin, chymotrypsin, thrombin and papain. Protease Inhibitors, detecting and measuring antibodies in human intestinal aspirate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Trinchieri, G., et al.: J. immunol., 116, 885 (1976); James G. T.: Anal. biochem., 86, 574 (1978); Kraut, D., et al.: Mol. Pharmacol., 57, 1243 (2000); Raulstron, D. L., et al.: J. Biol. Chem., 256, 7173 (1981); Sekar V., et al.: Biochem. biophys. Res. Commun., 89, 474 (1979); Hohmann, A., et al.: J. immunol. Methods, 64, 199 (1983); Umemura, A., et al.: Stroke, 23, 1163 (1992)

Formula: C₇H₇FO₂S

Color and Shape: Neat

Molecular weight: 174.19

Ref: TR-P337545

Phenylmethylsulfonyl fluoride

CAS: 329-98-6

PMSF is a serine protease inhibitor that irreversibly inhibits serine proteases by sulfonylation of the serine residue in the active site of the protease. It is widely used in protocols for the isolation of proteins.

Formula: C₇H₇FO₂S

Purity: Min. 99.0 Area-%

Molecular weight: 174.20 g/mol

Ref: 3D-P-4170

α-Toluenesulfonyl fluoride

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: 99%

Color and Shape: Solid, Crystalline

Molecular weight: 174.19

Ref: 10-F002462

Phenylmethane Sulphonyl Fluoride (PMSF) extrapure, 99%

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: min. 99%

Color and Shape: White to off-white, Crystalline powder, Clear

Molecular weight: 174.20

Ref: SR-87606

Phenylmethane Sulphonyl Fluoride (PMSF) for cell culture, 99%, Endotoxin (BET) 0.05EU/mg

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: min. 99%

Color and Shape: White to off-white, Crystalline powder, Clear

Molecular weight: 174.20

Ref: SR-77839

Phenylmethane Sulphonyl Fluoride (PMSF) for molecular biology, 99%

CAS: 329-98-6

Formula: C₇H₇FO₂S

Purity: min. 99%

Color and Shape: White to off-white, Crystalline powder, Clear

Molecular weight: 174.20

Ref: SR-84375