CAS 33037-46-6

Aloe-emodin 8-O-β-D-glucopyranoside

Description:

Aloe-emodin 8-O-β-D-glucopyranoside is a glycosylated derivative of aloe-emodin, a naturally occurring anthraquinone found in various species of the Aloe plant. This compound is characterized by its structure, which includes a glucopyranoside moiety attached to the 8-position of the aloe-emodin backbone. It exhibits a range of biological activities, including anti-inflammatory, antioxidant, and potential anticancer properties, making it of interest in pharmacological research. Aloe-emodin itself is known for its laxative effects and has been used in traditional medicine. The glycosylation in Aloe-emodin 8-O-β-D-glucopyranoside may influence its solubility, stability, and bioavailability compared to its aglycone form. This compound is typically studied in the context of natural product chemistry and its potential therapeutic applications. As with many natural compounds, its safety and efficacy are subjects of ongoing research, particularly regarding its mechanisms of action and potential side effects.

Formula: C₂₁H₂₀O₁₀

InChI: InChI=1S/C21H20O10/c22-6-8-4-10-14(11(24)5-8)18(27)15-9(16(10)25)2-1-3-12(15)30-21-20(29)19(28)17(26)13(7-23)31-21/h1-5,13,17,19-24,26,28-29H,6-7H2/t13-,17-,19+,20-,21-/m1/s1

InChI key: InChIKey=KIZBWUUJNJEYCM-JNHRPPPUSA-N

SMILES: O(C1=C2C(C(=O)C=3C(C2=O)=C(O)C=C(CO)C3)=CC=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Synonyms:

• Glucopyranoside, 8-hydroxy-6-(hydroxymethyl)-1-anthraquinonyl, β-D-
• 1-Hydroxy-3-hydroxymethyl-8-β-D-glucosyloxyanthraquinone
• 8-(β-D-Glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-9,10-anthracenedione
• 9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-
• Aloe-emodin-8-O-beta-D-glucopyranoside
• Aloe emodin 8-mono-β-D-glucoside

Aloe-emodin-8-O-β-D-glucopyranoside

CAS: 33037-46-6

Aloe-emodin-8-O-β-D-glucopyranoside

Purity: ≥98%

Molecular weight: 432.38g/mol

Ref: 54-BUP01107

Aloe-emodin-8-O-β-D-glucopyranoside

CAS: 33037-46-6

Formula: C₂₁H₂₀O₁₀

Molecular weight: 432.38

Ref: 7W-GY3533

Aloe-emodin-8-O-β-D-glucopyranoside

CAS: 33037-46-6

Formula: C₂₁H₂₀O₁₀

Purity: 95%~99%

Molecular weight: 432.381

Ref: BP-BP0147

Aloe-emodin-8-O-β-D-glucopyranoside

CAS: 33037-46-6

Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B)

Formula: C₂₁H₂₀O₁₀

Purity: 99.21% - 99.91%

Color and Shape: Solid

Molecular weight: 432.38

Ref: TM-TN1053

Aloe emodin 8-glucoside

CAS: 33037-46-6

Natural glycoside

Formula: C₂₁H₂₀O₁₀

Purity: ≥ 90.0 % (HPLC)

Molecular weight: 432.38

Ref: 5G-85718

Aloe Emodin 8-Glucoside

CAS: 33037-46-6

Aloe Emodin 8-Glucoside is a natural compound that belongs to the group of sennosides. It has been shown to have synergistic effects with insulin sensitivity, and can be used for the treatment of type 2 diabetes. Aloe Emodin 8-Glucoside also has laxative properties and can be used to treat constipation. It is thought that this drug may work by inhibiting phosphatases, which are enzymes that break down other enzymes. Aloe Emodin 8-Glucoside has been shown to inhibit ptp1b, which is an enzyme involved in the production of insulin and serotonin. This drug also binds to allosteric sites on protein kinase A (PKA), leading to increased levels of cAMP and decreased levels of cGMP in cells. Allosteric binding sites are those that do not directly bind with the ATP molecule but instead bind with another molecule like cAMP or cGMP. These

Formula: C₂₁H₂₀O₁₀

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 432.38 g/mol

Ref: 3D-IBA03746