CAS 330600-85-6

Peramivir

Description:

Peramivir is an antiviral medication primarily used for the treatment of influenza. It belongs to the class of neuraminidase inhibitors, which function by blocking the viral enzyme neuraminidase, thereby preventing the release of new viral particles from infected cells. This action helps to reduce the severity and duration of influenza symptoms. Peramivir is administered via intravenous infusion, making it particularly useful in cases where oral medications are not feasible, such as in hospitalized patients. The chemical structure of Peramivir includes a cyclopentane ring and a carboxylic acid group, contributing to its pharmacological properties. It has a relatively high bioavailability when administered intravenously and is generally well-tolerated, although potential side effects may include gastrointestinal disturbances and hypersensitivity reactions. The substance is also notable for its rapid onset of action, making it effective when administered early in the course of influenza infection. Overall, Peramivir represents an important therapeutic option in the management of severe influenza cases.

Formula: C₁₅H₂₈N₄O₄

InChI: InChI=1/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/m0/s1

InChI key: InChIKey=XRQDFNLINLXZLB-CKIKVBCHSA-N

SMILES: [C@@H](C(CC)CC)(NC(C)=O)[C@]1([C@H](NC(=N)N)C[C@H](C(O)=O)[C@H]1O)[H]

Synonyms:

• (1S,2R,3R,4R)-3-(1-acetamido-2-ethyl-butyl)-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid
• (1S,2R,3R,4R)-3-[(1S)-1-acetamido-2-ethyl-butyl]-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid
• (1S,2S,3R,4R)-3-((1S)-1-Acetamido-2-ethylbutyl)-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
• (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid
• (1S,2S,3R,4R)-3-[1(S)-(Acetylamino)-2-ethylbutyl]-4-[[amino(imino)methyl]amino]-2-hydroxycyclopentanecarboxylic acid
• (1S,2S,3S,4R)-3-((1S)-1-Acetamido-2-ethylbutyl)-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
• (1S,2S,3S,4R)-3-(1-acetamido-2-ethyl-butyl)-4-guanidino-2-hydroxy-cyclopentane-1-carboxylic acid
• (1S,2S,3S,4R)-3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(diaminomethylidene)amino]-2-hydroxycyclopentanecarboxylic acid
• Alpivab
• Bcx-1812
• Cyclopentanecarboxylic acid, 3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-, (1S,2S,3R,4R)-
• Peramivir
• Rapiacta
• Rapivab
• Rwj-270201
• (229614-55-5) peramivir
• Aids-114230
• PeraMivir(RWJ-270201,BCX-1812)
• (1S,2S,3R,4R)-3-((S)-1-AcetaMido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid
• (1S,2R,3R,4R)-3-(1-acetaMido-2-ethyl-butyl)-4-(diaMinoMethylideneaMino)-2-hydroxy-cyclopentane-1-car
• Peramivir(BCX-1812)
• PeraMiviv

(1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid

CAS: 330600-85-6

Formula: C₁₅H₂₈N₄O₄

Purity: %

Color and Shape: Solid

Molecular weight: 328.4072

Ref: IN-DA00C6H6

Peramivir

CAS: 330600-85-6

Formula: C₁₅H₂₈N₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 328.41

Ref: 4Z-P-124001

Peramivir

CAS: 330600-85-6

Peramivir

Purity: ≥98%

Molecular weight: 328.41g/mol

Ref: 54-BUP02374

Peramivir

CAS: 330600-85-6

Formula: C₁₅H₂₈N₄O₄

Molecular weight: 328.41

Ref: 7W-GP8743

Peramivir

CAS: 330600-85-6

Peramivir is a neuraminidase inhibitor used to treat influenza by preventing virus release from cells.

Formula: C₁₅H₂₈N₄O₄

Purity: 99.82%

Color and Shape: Solid

Molecular weight: 328.41

Ref: TM-T21339

(1S,2S,3R,4R)-3-((S)-1-Acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid

CAS: 330600-85-6

Formula: C₁₅H₂₈N₄O₄

Purity: 98.0%

Molecular weight: 328.413

Ref: 10-F496789

Peramivir

CAS: 330600-85-6

Applications A new antiviral agent for influenza treatment; it can be used as neuraminidase inhibitor for treating human and avian influenza.
References Whitley, R., et al.: Pediatr. Infect. Dis. J., 20, 127 (2001), Bright, R., et al.: Lancet., 366, 1175 (2005), Deyde, V., et al.: J. Infect. Dis., 196, 249 (2007), Lee, N., et al.: Clin. Infect. Dis., 46, 1323 (2008),

Formula: C₁₅H₂₈N₄O₄

Color and Shape: Neat

Molecular weight: 328.41

Ref: TR-P285500

Peramivir

CAS: 330600-85-6

Selective and potent inhibitor of sialidases (neuraminidases) in influenza A and B viruses. The compound binds tightly to the viral neuraminidase active site in late stages of viral life-cycle. It inhibits shedding sialic acids from host cell surface glycans, which interact with viral hemagglutinin, and consequently prevents release of new viral particles from the host cell surface.

Formula: C₁₅H₂₈N₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.41 g/mol

Ref: 3D-FP65126