CAS 330600-85-6
:Peramivir
Description:
Peramivir is an antiviral medication primarily used for the treatment of influenza. It belongs to the class of neuraminidase inhibitors, which function by blocking the viral enzyme neuraminidase, thereby preventing the release of new viral particles from infected cells. This action helps to reduce the severity and duration of influenza symptoms. Peramivir is administered via intravenous infusion, making it particularly useful in cases where oral medications are not feasible, such as in hospitalized patients. The chemical structure of Peramivir includes a cyclopentane ring and a carboxylic acid group, contributing to its pharmacological properties. It has a relatively high bioavailability when administered intravenously and is generally well-tolerated, although potential side effects may include gastrointestinal disturbances and hypersensitivity reactions. The substance is also notable for its rapid onset of action, making it effective when administered early in the course of influenza infection. Overall, Peramivir represents an important therapeutic option in the management of severe influenza cases.
Formula:C15H28N4O4
InChI:InChI=1/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/m0/s1
InChI key:InChIKey=XRQDFNLINLXZLB-CKIKVBCHSA-N
SMILES:[C@@H](C(CC)CC)(NC(C)=O)[C@]1([C@H](NC(=N)N)C[C@H](C(O)=O)[C@H]1O)[H]
Synonyms:- (1S,2R,3R,4R)-3-(1-acetamido-2-ethyl-butyl)-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid
- (1S,2R,3R,4R)-3-[(1S)-1-acetamido-2-ethyl-butyl]-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid
- (1S,2S,3R,4R)-3-((1S)-1-Acetamido-2-ethylbutyl)-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
- (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid
- (1S,2S,3R,4R)-3-[1(S)-(Acetylamino)-2-ethylbutyl]-4-[[amino(imino)methyl]amino]-2-hydroxycyclopentanecarboxylic acid
- (1S,2S,3S,4R)-3-((1S)-1-Acetamido-2-ethylbutyl)-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
- (1S,2S,3S,4R)-3-(1-acetamido-2-ethyl-butyl)-4-guanidino-2-hydroxy-cyclopentane-1-carboxylic acid
- (1S,2S,3S,4R)-3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(diaminomethylidene)amino]-2-hydroxycyclopentanecarboxylic acid
- Alpivab
- Bcx-1812
- Cyclopentanecarboxylic acid, 3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-, (1S,2S,3R,4R)-
- Peramivir
- Rapiacta
- Rapivab
- Rwj-270201
- (229614-55-5) peramivir
- Aids-114230
- PeraMivir(RWJ-270201,BCX-1812)
- (1S,2S,3R,4R)-3-((S)-1-AcetaMido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid
- (1S,2R,3R,4R)-3-(1-acetaMido-2-ethyl-butyl)-4-(diaMinoMethylideneaMino)-2-hydroxy-cyclopentane-1-car
- Peramivir(BCX-1812)
- PeraMiviv
- See more synonyms
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Peramivir
CAS:Applications A new antiviral agent for influenza treatment; it can be used as neuraminidase inhibitor for treating human and avian influenza.
References Whitley, R., et al.: Pediatr. Infect. Dis. J., 20, 127 (2001), Bright, R., et al.: Lancet., 366, 1175 (2005), Deyde, V., et al.: J. Infect. Dis., 196, 249 (2007), Lee, N., et al.: Clin. Infect. Dis., 46, 1323 (2008),Formula:C15H28N4O4Color and Shape:NeatMolecular weight:328.41Peramivir
CAS:Peramivir is a neuraminidase inhibitor used to treat influenza by preventing virus release from cells.Formula:C15H28N4O4Purity:99.90%Color and Shape:SolidMolecular weight:328.41(1S,2S,3R,4R)-3-((S)-1-Acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid
CAS:(1S,2S,3R,4R)-3-((S)-1-Acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acidFormula:C15H28N4O4Purity:98+%Molecular weight:328.41(1S,2S,3R,4R)-3-((S)-1-Acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid
CAS:Formula:C15H28N4O4Purity:98+%Molecular weight:328.413Peramivir
CAS:Selective and potent inhibitor of sialidases (neuraminidases) in influenza A and B viruses. The compound binds tightly to the viral neuraminidase active site in late stages of viral life-cycle. It inhibits shedding sialic acids from host cell surface glycans, which interact with viral hemagglutinin, and consequently prevents release of new viral particles from the host cell surface.
Formula:C15H28N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:328.41 g/mol(1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid
CAS:Formula:C15H28N4O4Purity:%Color and Shape:SolidMolecular weight:328.4072
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