CAS 332359-99-6

8-bromoguanosine hydrate

Description:

8-Bromoguanosine hydrate is a modified nucleoside that features a bromine atom substituted at the 8-position of the guanine base. This compound is characterized by its structural components, which include a ribose sugar linked to the guanine moiety. The presence of the bromine atom can influence the compound's biochemical properties, such as its interaction with nucleic acids and potential applications in molecular biology and medicinal chemistry. As a hydrate, it contains water molecules in its crystalline form, which can affect its solubility and stability. 8-Bromoguanosine hydrate is often studied for its role in nucleic acid research, particularly in the context of studying RNA and DNA interactions, as well as its potential therapeutic applications. The compound's unique properties may also make it a candidate for further exploration in drug development, especially in targeting specific biological pathways. Overall, 8-bromoguanosine hydrate exemplifies the diverse modifications that can occur in nucleoside chemistry, leading to varied biological activities.

Formula: C₁₀H₁₄BrN₅O₆

InChI: InChI=1/C10H12BrN5O5.H2O/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8;/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20);1H2/t2-,4-,5-,8-;/m1./s1

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2c3c(c(nc(=N)[nH]3)O)nc2Br)O1)O)O)O.O

8-Bromoguanosine hydrate, 97%

CAS: 332359-99-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₂BrN₅O₅

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream or pink

Molecular weight: 362.14

Ref: 02-L02992

8-BROMOGUANOSINE DIHYDRATE

CAS: 332359-99-6

Formula: C₁₀H₁₆BrN₅O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.1673

Ref: IN-DA003NHZ

8-Bromoguanosine hydrate

CAS: 332359-99-6

Formula: C₁₀H₁₂BrN₅O₅xH₂O

Molecular weight: 362.14

Ref: 7W-GN7333

8-Bromoguanosine hydrate

CAS: 332359-99-6

8-Bromoguanosine hydrate is a brominated form of guanosine. It is used as a marker for colorectal cancer in urine samples. 8-Bromoguanosine hydrate can be used to calibrate the results of chromatographic analyses and to identify metabolic disorders, such as fatty acid oxidation defects. The compound is also an endogenous ligand that interacts with adenosine receptors and may have pro-apoptotic effects on cancer cells by triggering their death. 8-Bromoguanosine hydrate has been shown to be more effective than other brominated nucleosides in inducing apoptosis in malignant cells, including colorectal carcinoma cells.

Formula: C₁₀H₁₂BrN₅O₅·xH₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 362.14 g/mol

Ref: 3D-NB28930