CAS 33419-42-0

Etoposide

Description:

Etoposide is a chemotherapeutic agent primarily used in the treatment of various cancers, including testicular cancer and small cell lung cancer. It is classified as a topoisomerase II inhibitor, which means it interferes with the enzyme responsible for DNA replication and repair, ultimately leading to cancer cell death. Etoposide is typically administered intravenously or orally and is known for its effectiveness in combination with other chemotherapy drugs. The compound has a molecular formula of C21H22O8 and a molecular weight of approximately 366.39 g/mol. Etoposide is characterized by its ability to induce apoptosis in cancer cells, making it a valuable tool in oncology. However, it can also cause side effects, including myelosuppression, gastrointestinal disturbances, and increased risk of secondary malignancies. Due to its mechanism of action, careful monitoring and management of dosage are essential to minimize toxicity while maximizing therapeutic efficacy. Overall, etoposide remains an important agent in the arsenal against certain malignancies.

Formula:C₂₉H₃₂O₁₃

InChI:InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1

InChI key:InChIKey=VJJPUSNTGOMMGY-MRVIYFEKSA-N

SMILES:O=C1[C@@]2([C@@H](C=3C([C@@H](O[C@@H]4O[C@]5([C@]([C@H](O)[C@H]4O)(O[C@H](C)OC5)[H])[H])[C@]2(CO1)[H])=CC6=C(C3)OCO6)C7=CC(OC)=C(O)C(OC)=C7)[H]

Synonyms:

(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-alpha-L-gulopyranoside
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-mannopyranoside
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1S)-ethylidene]-alpha-L-gulopyranoside
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1S)-ethylidene]-beta-D-mannopyranoside
(8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
4'-Demethyl-1-O-[4,6-O-(ethylidene)-β-D-glucopyranosyl]epipodophyllotoxin
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-β-D-glucoside
4'-Demethylepipodophyllotoxin-(4,6-O-(R)-Ethylidene-Beta-D-Glucopyranoside)
4-Demethylepipodophyllotoxin-Beta-D-Ethylideneglucoside
4′-Demethyl-1-O-[4,6-O-(ethylidene)-β-D-glucopyranosyl]epipodophyllotoxin
4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside)
4′-Demethylepipodophyllotoxin ethylidene-β-D-glucoside
Beposid
Bioposide
Celltop
EPE
Epipodophyllotoxin VP 16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-β-D-glucopyranoside
Epipodophyllotoxin, 4′-demethyl-, 4,6-O-ethylidene-β-D-glucopyranoside
Eposed
Eposin
Ethopul
Eto-Gry
Etoposid
Etoposido
Etosid
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahy dro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
Fytop
Fytosid
Lastet
Nsc 141540
Nzytop
Pyrano[3,2-d]-1,3-dioxin, furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one deriv.
Sintopozid
Topok
Toposar
Toposide
VP 16 (pharmaceutical)
VePesid
Vepesid J
Vp 16
Vp 16-123
Vp 16-213
Zuyeyidal
trans-Etoposide
Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
See more synonyms

Purity (%)

100

products per page.Found 30 products.

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Etoposide-d4
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33419-42-0
Applications Etoposide-d4, is the labeled analogue of Etoposide (E933750), a DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.
References Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996), Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996),
Formula:C₂₉H₂₈D₄O₁₃
Color and Shape:Neat
Molecular weight:592.58
Ref: TR-E933753
1mg
336.00€
VAT not included
10mg
2,153.00€
VAT not included
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Etoposide-d3
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33419-42-0
Applications A labelled DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.
References Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996), Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996),
Formula:C₂₉H₂₉D₃O₁₃
Color and Shape:Neat
Molecular weight:591.58
Ref: TR-E933752
1mg
382.00€
VAT not included
10mg
2,530.00€
VAT not included
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Etoposide
CAS:
- 33419-42-0
Etoposide is a cytotoxic drug used in cancer chemotherapy. It inhibits DNA replication through inhibition of DNA topoisomerase II, thus catalysing cell cycle arrest and apoptosis.
Formula:C₂₉H₃₂O₁₃
Purity:Min. 98 Area-%
Color and Shape:White Powder
Molecular weight:588.55 g/mol
Ref: 3D-ME09941
1g
300.00€
VAT not included
2g
435.00€
VAT not included
5g
620.00€
VAT not included
10g
834.00€
VAT not included
25g
1,226.00€
VAT not included
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Etoposide - Bio-X ™
CAS:
- 33419-42-0
Etoposide is a cytotoxic drug used in cancer chemotherapy. It inhibits DNA replication through inhibition of DNA topoisomerase II, thus catalysing cell cycle arrest and apoptosis.
Etoposide is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.
Formula:C₂₉H₃₂O₁₃
Purity:Min. 98 Area-%
Color and Shape:White Powder
Molecular weight:588.56 g/mol
Ref: 3D-BE164434
100mg
186.00€
VAT not included
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Etoposide-[13C,d3]
CAS:
- 33419-42-0
Ref: BE-MCD-7346
1mg
2,191.00€
VAT not included
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Etoposide (Standard)
CAS:
- 33419-42-0
Etoposide (Standard) is a reference standard for research and analysis in studies involving Etoposide. Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy.
Formula:C₂₉H₃₂O₁₃
Color and Shape:Solid
Molecular weight:588.56
Ref: TM-TMSM-3462
100mg
190.00€
VAT not included
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Etoposide-d4
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33419-42-0
Etoposide is a cytotoxic drug used in cancer chemotherapy. It inhibits DNA replication through inhibition of DNA topoisomerase II, thus catalysing cell cycle arrest and apoptosis. This compoud, Etoposide-d4, is a deuterated form of the drug.
Formula:C₂₉H₃₂O₁₃
Purity:Min. 95%
Ref: 3D-ME45909
5mg
1,058.00€
VAT not included
10mg
1,481.00€
VAT not included
25mg
2,576.00€
VAT not included
50mg
3,214.00€
VAT not included
100mg
5,268.00€
VAT not included
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Etoposide
CAS:
- 33419-42-0
Formula:C₂₉H₃₂O₁₃
Molecular weight:588.6
Ref: ST-EA-CP-E31000
10mg
To inquire
25mg
To inquire
50mg
To inquire
100mg
To inquire
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Etoposide
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33419-42-0
Formula:C₂₉H₃₂O₁₃
Color and Shape:Neat
Molecular weight:588.56
Ref: 86-MM0492.00
250mg
Discontinued
Request information
Discontinued product
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Etoposide RS
CAS:
- 33419-42-0
Color and Shape:White
Ref: 2K-1025000021
100mg
Discontinued
Request information
Discontinued product

CAS 33419-42-0

Etoposide

Etoposide-d4

Ref: TR-E933753

Etoposide-d3

Ref: TR-E933752

Etoposide

Ref: 3D-ME09941

Etoposide - Bio-X ™

Ref: 3D-BE164434

Etoposide-[13C,d3]

Ref: BE-MCD-7346

Etoposide (Standard)

Ref: TM-TMSM-3462

Etoposide-d4

Ref: 3D-ME45909

Etoposide

Ref: ST-EA-CP-E31000

Etoposide

Ref: 86-MM0492.00

Etoposide RS

Ref: 2K-1025000021