CAS 33818-15-4
:Citicoline sodium
Description:
Citicoline sodium, also known as cytidine diphosphate choline, is a naturally occurring compound that plays a crucial role in the synthesis of phospholipids, particularly phosphatidylcholine, which is essential for cell membrane integrity and function. It is a sodium salt of citicoline, characterized by its ability to enhance cognitive function and support neuronal health. Citicoline is often used as a nootropic agent, believed to improve memory and cognitive performance, particularly in conditions such as stroke, traumatic brain injury, and age-related cognitive decline. The substance is water-soluble, making it easily absorbed in the gastrointestinal tract. It is generally well-tolerated, with a favorable safety profile, and side effects are typically mild, including gastrointestinal discomfort. Citicoline sodium is available in various formulations, including oral tablets and injectable forms, and is often utilized in dietary supplements and pharmaceutical preparations aimed at enhancing cognitive function and neuroprotection. Its mechanism of action involves the modulation of neurotransmitter levels and the promotion of neuronal membrane repair.
Formula:C14H26N4O11P2·Na
InChI:InChI=1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/t9-,11-,12-,13-;/m1./s1
InChI key:InChIKey=GBRJGMTWFZWCCU-OCMLZEEQSA-N
SMILES:O[C@H]1[C@@H](O[C@H](COP(OP(OCC[N+](C)(C)C)(=O)[O-])(=O)O)[C@H]1O)N2C(=O)N=C(N)C=C2.[Na]
Synonyms:- Acticolin
- Brassel
- Cebroton
- CerAxon
- Choline, hydroxide, monoester with cytidine 5′-(trihydrogen pyrophosphate), inner salt, monosodium salt
- Cidifos
- Citicoline Sodium
- Cytidine 5'-(Trihydrogen Diphosphate) P'-(2-(Trimethylammonio)Ethyl) Ester Inner Salt Monosodium Salt
- Cytidine 5′-(trihydrogen diphosphate), P′-[2-(trimethylammonio)ethyl] ester, hydroxide, inner salt, monosodium salt
- Cytidine 5′-(trihydrogen diphosphate), P′-[2-(trimethylammonio)ethyl] ester, inner salt, sodium salt (1:1)
- Flussorex
- Gerolin
- IP 302 sodium
- Logan
- Neurotron
- Sinkron
- Strolin
- See more synonyms
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Found 14 products.
Cytidine 5'-Diphosphocholine Sodium Salt
CAS:Formula:C14H25N4NaO11P2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:510.31Cytidine-5'-diphosphocholine sodium salt
CAS:<p>Intermediate in the synthesis of phosphatidylcholine; also a phospholipase inhibitor</p>Formula:C14H25N4NaO11P2Color and Shape:White, Powder or crystals or crystalline powderMolecular weight:510.31Citicoline Sodium
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C14H25N4NaO11P2Color and Shape:White PowderMolecular weight:510.08928sodium 2-(trimethylazaniumyl)ethyl ({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
CAS:Formula:C14H25N4NaO11P2Purity:97%Color and Shape:SolidMolecular weight:510.3058Citicoline sodium
CAS:<p>Citicoline sodium aids in making phosphatidylcholine and acetylcholine, protects the brain from trauma, and improves memory.</p>Formula:C14H25N4NaO11P2Purity:99.26% - 99.37%Color and Shape:White SolidMolecular weight:510.31Citicoline Sodium Salt (CDP-Choline Sodium Salt)
CAS:Formula:C14H25N4O11P2·NaMolecular weight:487.32 22.99Citicoline sodium salt
CAS:Formula:C14H25N4NaO11P2·xH2OPurity:≥ 98.0% (anhydrous basis)Color and Shape:White to almost white crystalline powderMolecular weight:511.31 (anhydrous)Citicoline Sodium Salt
CAS:<p>Applications Naturally occurring nucleotide; intermediate in the major pathway of lecitin biosynthesis. Neuroprotective. It is used in the treatment of ischemic stroke and head trauma. Neuroprotective product. Citicholine exhibits protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Recently showed efficacy against dementia when given with AchEIs (Acetylcholinesterase inhibitor) (1). Depicts Neuroprotective, acnticonvulsant activity and sedative effect at a dose of 150mg/kg in rats. (2). Showed protection against aluminum induced cognitive impairment in rats reducing elevated glutamate level, oxidative stress and NO overproduction in the hippocampus.<br>References Castagna A, et al. Clin Drug Investig. 2016 Sep 1 Abdolmaleki A, et al. 2016. Eur J Pharmacol. Oct 15;789:275-9Abdel-Zaher AO et al. Toxicol Ind Health. 2016 May 13<br></p>Formula:C14H25N4O11P2·NaColor and Shape:WhiteMolecular weight:510.31Citicoline-d9 Sodium Salt
CAS:Controlled Product<p>Applications Labelled Citicoline (C508050). Naturally occurring nucleotide; intermediate in the major pathway of lecitin biosynthesis. Neuroprotective. It is used in the treatment of ischemic stroke and head trauma.<br>References Kennedy, E.P., et al.: J. Biol. Chem., 222, 185 (1956), Rao, A., et al.: J. Neurosci. Res., 58, 697 (1999), Wurtman, R., et al.: Biochem. Pharmacol., 60, 989 (2000),<br></p>Formula:C14D9H16N4NaO11P2Color and Shape:NeatMolecular weight:519.361Citicoline sodium
CAS:<p>Citicoline is a complex organic molecule, a form of B-vitamin choline that acts as an intermediate in many biosynthetic pathways, for example, in the biosynthesis of cell membrane phospholipids. As a dietary supplement, citicoline is a source of choline and cytidine, two components that are quickly absorbed in the intestine and across the blood-brain barrier. The neuroprotective properties of citicoline improves mental performance increasing the levels of other brain-related chemicals like dopamine and norepinephrine, helping with recovery in stroke patients, reducing memory loss due to aging and improving vision in patients with glaucoma.</p>Formula:C14H26N4O11P2•NaPurity:Min. 98.0 Area-%Color and Shape:White To Off-White SolidMolecular weight:511.31 g/mol
