CAS 34218-84-3

5-Iodo-2′-O-methyluridine

Description:

5-Iodo-2′-O-methyluridine is a modified nucleoside that features an iodine atom at the 5-position of the uridine base and a methoxy group at the 2′ position of the ribose sugar. This compound is characterized by its unique structural modifications, which can influence its biological activity and stability. The presence of the iodine atom can enhance the compound's ability to interact with nucleic acids, potentially affecting its role in RNA synthesis and function. The 2′-O-methyl modification is known to confer resistance to ribonucleases, thereby increasing the stability of the nucleoside in biological systems. 5-Iodo-2′-O-methyluridine is often studied for its potential applications in molecular biology, particularly in the development of antiviral agents and as a tool in RNA research. Its chemical properties, such as solubility and reactivity, may vary depending on the solvent and conditions used in experiments. Overall, this compound represents a significant interest in the field of nucleoside chemistry and its applications in therapeutic development.

Formula: C₁₀H₁₃IN₂O₆

InChI: InChI=1S/C10H13IN2O6/c1-18-7-6(15)5(3-14)19-9(7)13-2-4(11)8(16)12-10(13)17/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6-,7-,9-/m1/s1

InChI key: InChIKey=PLVDDNNLEWFJNQ-JXOAFFINSA-N

SMILES: O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(I)=C2

Synonyms:

• 2'-(O-Methyl)-5-Iodouridine
• 2'-O-methyl-5-Iodo-Uridine
• 5-Iodo-2'-O-Methyluridine
• Uridine, 5-iodo-2′-O-methyl-

2'-(O-METHYL)-5-IODOURIDINE

CAS: 34218-84-3

Formula: C₁₀H₁₃IN₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 384.1245

Ref: IN-DA00C0LW

2'-O-Methyl-5-iodouridine

CAS: 34218-84-3

2'-O-Methyl-5-iodouridine

Purity: ≥98%

Molecular weight: 384.12g/mol

Ref: 54-BUP15819

2'-O-Methyl-5-iodouridine

CAS: 34218-84-3

2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a

Formula: C₁₀H₁₃IN₂O₆

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 384.12

Ref: TM-TNU0630

5-Iodo-2'-O-methyluridine

CAS: 34218-84-3

5-Iodo-2'-O-methyluridine is a novel antiviral drug that inhibits replication of DNA and RNA viruses. It is chemically synthesized from 2' deoxyuridine monophosphate, which is modified to create the 5-iodo derivative. The modification at the 5th position of the uracil ring prevents the incorporation of methylation into DNA and RNA, which can lead to cancerous growths. This compound has been shown to be an excellent activator for DNA synthesis in vitro. It has also been shown to have anticancer properties in vitro and in vivo.

Formula: C₁₀H₁₃IN₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 384.12 g/mol

Ref: 3D-NI06234