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CAS 34218-84-3

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5-Iodo-2′-O-methyluridine

Description:
5-Iodo-2′-O-methyluridine is a modified nucleoside that features an iodine atom at the 5-position of the uridine base and a methoxy group at the 2′ position of the ribose sugar. This compound is characterized by its unique structural modifications, which can influence its biological activity and stability. The presence of the iodine atom can enhance the compound's ability to interact with nucleic acids, potentially affecting its role in RNA synthesis and function. The 2′-O-methyl modification is known to confer resistance to ribonucleases, thereby increasing the stability of the nucleoside in biological systems. 5-Iodo-2′-O-methyluridine is often studied for its potential applications in molecular biology, particularly in the development of antiviral agents and as a tool in RNA research. Its chemical properties, such as solubility and reactivity, may vary depending on the solvent and conditions used in experiments. Overall, this compound represents a significant interest in the field of nucleoside chemistry and its applications in therapeutic development.
Formula:C10H13IN2O6
InChI:InChI=1S/C10H13IN2O6/c1-18-7-6(15)5(3-14)19-9(7)13-2-4(11)8(16)12-10(13)17/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6-,7-,9-/m1/s1
InChI key:InChIKey=PLVDDNNLEWFJNQ-JXOAFFINSA-N
SMILES:O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(I)=C2
Synonyms:
  • 2'-(O-Methyl)-5-Iodouridine
  • 2'-O-methyl-5-Iodo-Uridine
  • 5-Iodo-2'-O-Methyluridine
  • Uridine, 5-iodo-2′-O-methyl-
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