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CAS 34661-75-1

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Urapidil

Description:
Urapidil is a pharmaceutical compound primarily used as an antihypertensive agent. It functions as an alpha-1 adrenergic receptor antagonist and a partial agonist at serotonin receptors, which contributes to its blood pressure-lowering effects. Urapidil is characterized by its ability to reduce peripheral vascular resistance without significantly affecting heart rate, making it beneficial for treating hypertension, particularly in patients with heart failure or those at risk of cardiovascular events. The compound is typically administered orally or intravenously, depending on the clinical scenario. Its pharmacokinetics include rapid absorption and a relatively short half-life, necessitating careful dosing to maintain therapeutic effects. Urapidil is generally well-tolerated, but potential side effects may include dizziness, fatigue, and gastrointestinal disturbances. As with any medication, its use should be guided by a healthcare professional, considering individual patient factors and potential drug interactions. Overall, Urapidil represents a valuable option in the management of hypertension, particularly in specific patient populations.
Formula:C20H29N5O3
InChI:InChI=1S/C20H29N5O3/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3/h4-5,7-8,15,21H,6,9-14H2,1-3H3
InChI key:InChIKey=ICMGLRUYEQNHPF-UHFFFAOYSA-N
SMILES:O(C)C1=C(C=CC=C1)N2CCN(CCCNC=3N(C)C(=O)N(C)C(=O)C3)CC2
Synonyms:
  • 2,4(1H,3H)-Pyrimidinedione, 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-
  • 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
  • 6-[[3-[4-(2-Methoxyphenyl)-1-Piperazinyl]Propyl]Amino]-1,3-Dimethyluracil
  • 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]-propyl]amino]1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
  • B 66256
  • Ebrantil
  • Eupressyl
  • Mediatensyl
  • NSC 310405
  • Urapidil hcl
  • See more synonyms
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Found 15 products.