CAS 3471-05-4
:Anabaseine
Description:
Anabaseine is a naturally occurring alkaloid derived from the plant species of the genus Nicotiana, particularly tobacco. It is a potent agonist of nicotinic acetylcholine receptors, which are critical for neurotransmission in both the central and peripheral nervous systems. Anabaseine is structurally related to nicotine, featuring a pyridine ring and an amine group, which contribute to its biological activity. The compound exhibits neuroprotective properties and has been studied for its potential therapeutic applications in neurodegenerative diseases. Anabaseine is typically found in low concentrations in tobacco and has been investigated for its effects on cognitive function and memory enhancement. Its pharmacological profile includes the ability to modulate synaptic transmission and influence neuronal excitability. However, due to its association with tobacco, the implications of its use and potential toxicity are subjects of ongoing research. As with many alkaloids, the safety and efficacy of anabaseine in clinical settings require careful evaluation.
Formula:C10H12N2
InChI:InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8H,1-2,5,7H2
InChI key:InChIKey=AUBPMADJYNSPOA-UHFFFAOYSA-N
SMILES:C=1(C=CC=NC1)C=2CCCCN2
Synonyms:- Anabaseine
- 2,3′-Bipyridine, 3,4,5,6-tetrahydro-
- 3,4,5,6-Tetrahydro-2,3′-bipyridine
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Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Color and Shape:SolidMolecular weight:160.22
