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CAS 3483-12-3

:

Dithiothreitol

Description:
Dithiothreitol (DTT), with the CAS number 3483-12-3, is a small-molecule reducing agent commonly used in biochemistry and molecular biology. It is characterized by its ability to break disulfide bonds in proteins, thereby maintaining proteins in their reduced state. DTT is a colorless, crystalline solid that is soluble in water and has a relatively low molecular weight. Its chemical structure features two thiol (-SH) groups, which are responsible for its reducing properties. DTT is often employed in protein purification, enzyme assays, and studies involving protein folding and stability. It is important to note that DTT can be sensitive to oxidation, and its effectiveness can diminish over time when exposed to air. Additionally, while DTT is widely used, it can interfere with certain assays and should be used with caution in experiments involving sensitive reagents. Overall, DTT is a valuable tool in the study of protein chemistry and redox biology.
Formula:C4H10O2S2
InChI:InChI=1/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/s2
InChI key:InChIKey=VHJLVAABSRFDPM-SEFKMRKONA-N
SMILES:[C@H]([C@@H](CS)O)(CS)O
Synonyms:
  • (.+-.)-1,4-Dimercapto-2,3-butanediol
  • (.+-.)-Dithiothreitol
  • (2S,3S)-1,4-disulfanylbutane-2,3-diol
  • (R*,R*)-1,4-Dimercapto-2,3-butanediol
  • (R*,R*)-1,4-Dimercaptobutan-2,3-diol
  • (R*,R*)-1,4-Dimercaptobutane-2,3-diol
  • (R*,R*)-1,4-dimercaptobutano-2,3-diol
  • (R,R)-Dithiothreitol
  • 1,4-Dithio-<span class="text-smallcaps">DL</span>-threitol
  • 1,4-Dithio-DL-threitol
  • See more synonyms
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