CAS 3483-12-3: Dithiothreitol

Description: Dithiothreitol (DTT), with the CAS number 3483-12-3, is a small-molecule reducing agent commonly used in biochemistry and molecular biology. It is characterized by its ability to break disulfide bonds in proteins, thereby maintaining proteins in their reduced state. DTT is a colorless, crystalline solid that is soluble in water and has a relatively low molecular weight. Its chemical structure features two thiol (-SH) groups, which are responsible for its reducing properties. DTT is often employed in protein purification, enzyme assays, and studies involving protein folding and stability. It is important to note that DTT can be sensitive to oxidation, and its effectiveness can diminish over time when exposed to air. Additionally, while DTT is widely used, it can interfere with certain assays and should be used with caution in experiments involving sensitive reagents. Overall, DTT is a valuable tool in the study of protein chemistry and redox biology.

Formula: C₄H₁₀O₂S₂

InChI: InChI=1/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/s2

InChI key: InChIKey=VHJLVAABSRFDPM-SEFKMRKONA-N

SMILES: OC(CS)C(O)CS

Synonyms:

• (.+-.)-1,4-Dimercapto-2,3-butanediol
• (.+-.)-Dithiothreitol
• (2S,3S)-1,4-disulfanylbutane-2,3-diol
• (R*,R*)-1,4-Dimercapto-2,3-butanediol
• (R*,R*)-1,4-Dimercaptobutan-2,3-diol
• (R*,R*)-1,4-Dimercaptobutane-2,3-diol
• (R*,R*)-1,4-dimercaptobutano-2,3-diol
• (R,R)-Dithiothreitol
• 1,4-Dithio-<span class="text-smallcaps">DL</span>-threitol
• 1,4-Dithio-DL-threitol
• 1,4-Dithio-Dl-Threitol Sol.
• 1,4-Dithio-l-threitol
• 1,4-Dithiothreitol
• 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-
• 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-
• 2,3-Butanediol, 1,4-dimercapto-, D-threo-
• <span class="text-smallcaps">DL</span>-1,4-Dimercapto-2,3-dihydroxybutane
• <span class="text-smallcaps">DL</span>-1,4-Dithiothreitol
• <span class="text-smallcaps">DL</span>-Dithiothreitol
• Cleland reagent
• Cleland regent
• Cleland's reagent
• Clelands REDUCTACRYL
• Clelands reagent
• D-1,4-Dithiothreitol
• D-Dtt
• D-threo-1,4-Dimercapto-2,3-butanediol
• DL-1,4-Dimercapto-2,3-dihydroxybutane
• DL-1,4-Dithiothreitol
• DL-Dithothreitol
• DTT
• DTT (threitol derivative)
• Dithiothreitol (Dtt) Sequencing Grade
• Dithiothreitol Molecular Biology*Reagent
• DithiothreitollelandsReagenz
• Dithithreitol
• L-Dtt
• Mucolyse
• Reagents, Cleland's
• Sputolysin
• Threitol, 1,4-dithio-
• Wr 34678
• rac-Dithiothreitol
• rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
• threo-1,4-Dimercapto-2,3-butanediol
• threo-2,3-Dihydroxy-1,4-butanedithiol
• threo-2,3-Dihydroxy-1,4-dithiolbutane

rac Dithiothreitol

CAS: 3483-12-3

Applications Dithiothreitol is a redox reagent commonly used as a reducing agent for thiolated DNA. …

• Formula: C₄H₁₀O₂S₂
• Color and Shape: Neat
• Molecular weight: 154.25

1,4-Dithiothreitol

CAS: 3483-12-3

Dithiothreitol, also known as DTT and Cleland's reagent, is a broadly used disulfide reducing agent …

• Formula: C₄H₁₀O₂S₂
• Molecular weight: 154.25 g/mol

Dithiothreitol

CAS: 3483-12-3

Dithiothreitol, also known as DTT and Cleland’s reagent, is a broadly used disulfide reducing agent …

• Formula: C₄H₁₀O₂S₂
• Color and Shape: Powder
• Molecular weight: 154.25 g/mol

DL-Dithiothreitol (DTT) ExiPlus, Multi-Compendial, 98%

CAS: 3483-12-3

• Formula: C₄H₁₀O₂S₂
• Purity: min. 98%
• Color and Shape: White, Crystalline hygroscopic powder, Clear, Colourless
• Molecular weight: 154.24

DL-Dithiothreitol (DTT) extrapure, 98%

CAS: 3483-12-3

• Formula: C₄H₁₀O₂S₂
• Purity: min. 98%
• Color and Shape: White, Crystalline hygroscopic powder, Clear, Colourless
• Molecular weight: 154.24

DL-Dithiothreitol (DTT) for cell culture, 98%, Endotoxin (BET) 1EU/mg

CAS: 3483-12-3

• Formula: C₄H₁₀O₂S₂
• Purity: min. 98%
• Color and Shape: White, Crystalline hygroscopic powder, Clear, Colourless
• Molecular weight: 154.24

DL-Dithiothreitol (DTT) for molecular biology, 98%

CAS: 3483-12-3

• Formula: C₄H₁₀O₂S₂
• Purity: min. 98%
• Color and Shape: White, Crystalline hygroscopic powder, Clear, Colourless
• Molecular weight: 154.24

Dithiothreitol, 1M aqueous solution

CAS: 3483-12-3

1M aqueous solution

• Formula: C₄H₁₀O₂S₂
• Purity: Min. 95%
• Color and Shape: Clear Liquid
• Molecular weight: 154.25 g/mol

1,4-Dithiothreitol

CAS: 3483-12-3

Dithiothreitol, also known as DTT and Cleland’s reagent, is a broadly used disulfide reducing agent …

• Formula: C₄H₁₀O₂S₂
• Molecular weight: 154.25 g/mol