CAS 352-11-4

4-Fluorobenzyl chloride

Description:

4-Fluorobenzyl chloride, with the CAS number 352-11-4, is an organic compound characterized by the presence of a fluorine atom and a chlorine atom attached to a benzyl group. It is a colorless to pale yellow liquid with a distinctive aromatic odor. The compound is known for its reactivity, particularly due to the presence of the electrophilic benzyl chloride moiety, which makes it useful in various organic synthesis applications, including the preparation of pharmaceuticals and agrochemicals. Its molecular formula is C7H6ClF, and it has a relatively low boiling point, indicating that it can exist as a volatile substance under standard conditions. 4-Fluorobenzyl chloride is soluble in organic solvents but has limited solubility in water. Safety precautions are necessary when handling this compound, as it can be irritating to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from incompatible substances is essential to maintain its stability and prevent hazardous reactions.

Formula: C₇H₆ClF

InChI: InChI=1S/C7H6ClF/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2

InChI key: InChIKey=IZXWCDITFDNEBY-UHFFFAOYSA-N

SMILES: C(Cl)C1=CC=C(F)C=C1

Synonyms:

• 1-(Chloromethyl)-4-Fluoro Benzene
• 1-(Chloromethyl)-4-Fluoro-Benzen
• 1-(Chloromethyl)-4-Fluorobenzene
• 4-Fluoro-1-(chloromethyl)benzene
• 4-Fluorophenylmethyl chloride
• Benzene, 1-(chloromethyl)-4-fluoro-
• Ethyl 3,3,3-Trifluoropropanoate
• NSC 25084
• P-Fluorobenzyl Chloride
• Para-Fluorobenzyl chloride
• Toluene, α-chloro-p-fluoro-
• alpha-Chloro-4-fluorotoluene
• alpha-Chloro-p-fluorotoluene
• α-Chloro-4-fluorotoluene
• α-Chloro-p-fluorotoluene

4-Fluorobenzyl Chloride

CAS: 352-11-4

Formula: C₇H₆ClF

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 144.57

Ref: 3B-F0204

4-Fluorobenzyl chloride, 99%

CAS: 352-11-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₆ClF

Purity: 99%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 144.57

Ref: 02-A14686

4-Fluorobenzyl chloride

CAS: 352-11-4

4-Fluorobenzyl chloride

Formula: C₇H₆ClF

Purity: 99%

Color and Shape: Colourless Liquid

Molecular weight: 144.57394

Ref: 54-PC3720

4-Fluorobenzyl-α,α-d2Chloride

CAS: 1219804-18-8, 352-11-4

Formula: FC₆H₄CD₂Cl

Purity: 98 atom % D

Color and Shape: Colourless Liquid

Molecular weight: 146.02676

Ref: 3U-D6077

4-Fluorobenzyl-2,3,5,6-d4Chloride

CAS: 1219804-10-0, 352-11-4

Formula: FC₆D₄CH₂Cl

Purity: 98 atom % D

Color and Shape: Colourless Liquid

Molecular weight: 148.03931

Ref: 3U-D6078

4-Fluorobenzyl-d6 Chloride

CAS: 1219804-13-3, 352-11-4

Formula: FC₆D₄CD₂Cl

Purity: 98 atom % D

Color and Shape: Colourless Liquid

Molecular weight: 150.05187

Ref: 3U-D6079

1-(Chloromethyl)-4-fluorobenzene

CAS: 352-11-4

Formula: C₇H₆ClF

Purity: 98%

Color and Shape: Liquid

Molecular weight: 144.5739

Ref: IN-DA003LF8

4-Fluorobenzyl chloride

CAS: 352-11-4

Formula: C₇H₆ClF

Molecular weight: 144.57

Ref: 4Z-B-139035

1-(Chloromethyl)-4-fluorobenzene

CAS: 352-11-4

1-(Chloromethyl)-4-fluorobenzene

Formula: C₇H₆ClF

Purity: 98%

Molecular weight: 144.57

Ref: IN-DG33356

4-Fluorobenzyl chloride

CAS: 352-11-4

Formula: C₇H₆ClF

Purity: 99%

Color and Shape: Liquid

Molecular weight: 144.57

Ref: 10-F006201

p-Fluorobenzyl Chloride

Controlled Product

CAS: 352-11-4

Applications p-Fluorobenzyl Chloride is a chemical intermediate in the synthesis of various pharmaceutical and agricultural goods.
References Wang, J., et al.: J. Agr. Food. Chem., 59, 9892 (2011); Wang, J.M., et al.: J. Chem. Info. Model., 47, 1395 (2007); Yang, E., et al.: Rapid. Commu. Mass. Spectro., 19, 759 (2005); Cronin, M.T.D., et al.: Sci. Total. Environ., 204, 75 (1997);

Formula: C₇H₆ClF

Color and Shape: Neat

Molecular weight: 144.57

Ref: TR-F588360

4-Fluorobenzyl chloride

CAS: 352-11-4

4-Fluorobenzyl chloride (4FBCl) is a fluorinated benzyl chloride that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4FBCl inhibits the growth of bacteria by reacting with sodium carbonate to form a molecule with chlorine atoms. 4FBCl has been shown to have cancer-fighting properties and is used as a treatment for malignant tumors. It also has anti-inflammatory properties, which are due to its ability to inhibit the production of growth factors. 4FBCl also has fluorescence properties and can be used as a fluorescent probe in certain reactions involving malonic acid or Friedel-Crafts reactions.

Formula: C₇H₆ClF

Purity: Min. 95%

Molecular weight: 144.57 g/mol

Ref: 3D-FF34655