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CAS 352-33-0

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1-Chloro-4-fluorobenzene

Description:
1-Chloro-4-fluorobenzene, with the CAS number 352-33-0, is an aromatic halogenated compound characterized by the presence of both chlorine and fluorine substituents on a benzene ring. Specifically, the chlorine atom is located at the first position and the fluorine atom at the fourth position, making it a para-substituted derivative of benzene. This compound is typically a colorless to pale yellow liquid with a distinctive aromatic odor. It is moderately soluble in water but more soluble in organic solvents such as ethanol and ether. 1-Chloro-4-fluorobenzene is known for its applications in organic synthesis, particularly as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Its chemical stability and reactivity are influenced by the electronegative halogen atoms, which can participate in various substitution reactions. Safety precautions are necessary when handling this compound, as it may pose health risks through inhalation or skin contact.
Formula:C6H4ClF
InChI:InChI=1S/C6H4ClF/c7-5-1-3-6(8)4-2-5/h1-4H
InChI key:InChIKey=RJCGZNCCVKIBHO-UHFFFAOYSA-N
SMILES:ClC1=CC=C(F)C=C1
Synonyms:
  • 1,4-Fluorochlorobenzene
  • 1-Chloro-4-Fluoro-Benzen
  • 1-Chloro-4-fluorobenzene
  • 1-Fluoro-4-chlorobenzene
  • 4-Chlorofluorobenzene
  • 4-Chlorofluorobenzene 99% (Gc)
  • 4-Fluoro-1-chlorobenzene
  • 4-Fluorochlorobenzene
  • 4-Fluorophenyl chloride
  • Benzene, 1-chloro-4-fluoro-
  • See more synonyms
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