CAS 3520-14-7

D-Tetrahydropalmatine

Description:

D-Tetrahydropalmatine (CAS 3520-14-7) is an alkaloid derived from the plant *Corydalis yanhusuo*, commonly used in traditional medicine. It is characterized by its structural formula, which includes a tetrahydroisoquinoline core, contributing to its pharmacological properties. D-Tetrahydropalmatine is known for its potential analgesic and sedative effects, making it of interest in pain management and anxiety treatment. It exhibits a moderate affinity for various neurotransmitter receptors, including dopamine and opioid receptors, which may underlie its therapeutic effects. The compound is typically found in a crystalline form and is soluble in organic solvents, with limited solubility in water. Its safety profile and efficacy are subjects of ongoing research, particularly regarding its potential for addiction and side effects. As with many natural products, the extraction and purification processes can influence its bioactivity and potency, making standardization important for clinical applications. Overall, D-Tetrahydropalmatine represents a promising area of study in pharmacognosy and medicinal chemistry.

Formula: C₂₁H₂₅NO₄

InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m1/s1

InChI key: AEQDJSLRWYMAQI-QGZVFWFLSA-N

SMILES: COC1=C(C2=C(C[C@@H]3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC

D-Tetrahydropalmatine

CAS: 3520-14-7

Formula: C₂₁H₂₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 355.4275

Ref: IN-DA00C7VG

D-Tetrahydropalmatine

CAS: 3520-14-7

Formula: C₂₁H₂₅NO₄

Molecular weight: 355.43

Ref: 7W-GY4589

D-tetrahydropalmatine

CAS: 3520-14-7

D-tetrahydropalmatine

Formula: C₂₁H₂₅NO₄

Purity: ≥98%

Molecular weight: 355.43

Ref: 54-BUP09897

D-Tetrahydropalmatine

CAS: 3520-14-7

Formula: C₂₁H₂₅NO₄

Purity: 95%~99%

Molecular weight: 355.434

Ref: BP-BP0517

D-Tetrahydropalmatine

Controlled Product

CAS: 3520-14-7

Applications D-Tetrahydropalmatine is an alkaloid isolated from a traditional Chinese herb Rhizoma Corydalis (yanhusuo). D-Tetrahydropalmatine inhibits dopamine and serotonin uptake of synaptosomes in the rat brain. D-Tetrahydropalmatine also shows inhibitory effects on acetylcholinesterase and butyrylcholinesterase.
References Xu, S.X. et al.: Zhong. Yao Li Xue Bao, 8, 207 (1987); Chlebek, J. et al.: Nat. Prod. Comm., 6, 607 (2011); Hong, Z. et al.: Biopharm. Drug Dispos., 27, 111 (2006);

Formula: C₂₁H₂₅NO₄

Color and Shape: Neat

Molecular weight: 355.43

Ref: TR-T294160

D-tetrahydropalmatine

CAS: 3520-14-7

D-Tetrahydropalmatine inhibits OCT1, reducing MCT uptake and hepatocyte damage in MDCK-hOCT1 cells and rat livers.

Formula: C₂₁H₂₅NO₄

Purity: 99.34%

Color and Shape: Yellow Solid

Molecular weight: 355.4275

Ref: TM-T4S0779