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CAS 35303-76-5

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4-(2-Aminoethyl)benzenesulfonamide

Description:
4-(2-Aminoethyl)benzenesulfonamide, also known as a sulfonamide compound, is characterized by its sulfonamide functional group (-SO2NH2) attached to a benzene ring, which is further substituted with an aminoethyl group. This structure imparts both hydrophilic and hydrophobic properties, making it soluble in polar solvents while retaining some lipophilicity due to the aromatic ring. The compound typically exhibits a white to off-white crystalline appearance and has a moderate melting point. It is known for its potential biological activity, particularly in medicinal chemistry, where sulfonamides have been utilized as antibacterial agents. The aminoethyl side chain can participate in hydrogen bonding, enhancing its interaction with biological targets. Additionally, the presence of the sulfonamide group contributes to its acidity, allowing it to act as a weak acid in solution. Overall, 4-(2-Aminoethyl)benzenesulfonamide is a versatile compound with applications in pharmaceuticals and biochemistry, particularly in the development of drugs targeting bacterial infections.
Formula:C8H12N2O2S
InChI:InChI=1S/C8H12N2O2S/c9-6-5-7-1-3-8(4-2-7)13(10,11)12/h1-4H,5-6,9H2,(H2,10,11,12)
InChI key:InChIKey=FXNSVEQMUYPYJS-UHFFFAOYSA-N
SMILES:S(N)(=O)(=O)C1=CC=C(CCN)C=C1
Synonyms:
  • 2-(4-Sulfamoylphenyl)ethylamine
  • 2-[4-(Aminosulfonyl)phenyl]ethylamine
  • 4-(2-Aminoethyl)Benzene Sulfonmide
  • 4-(2-Aminoethyl)Benzene Sulphonamide
  • 4-(2-Aminoethyl)Benzenesulfonamide (Intermediate Of Glibenclamide,Glipizide,Gliquidone)
  • 4-(2-Aminoethyl)benzensulfonamide
  • 4-(2-Aminoethyl)benzesulfonamide
  • 4-(2-Ethylamino) Benzene Sulfonamide
  • 4-(Aminosulfonyl)phenethylamine
  • 4-Aminoethyl benzenesulfonamide
  • See more synonyms
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