CAS 353262-04-1

NS-6180

CAS: 353262-04-1

Formula: C₁₆H₁₂F₃NOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.3328

Ref: IN-DA00C6GW

4-[[3-(Trifluoromethyl)phenyl]Methyl]-2H-1,4-Benzothiazin-3(4H)-One

CAS: 353262-04-1

4-[[3-(Trifluoromethyl)phenyl]Methyl]-2H-1,4-Benzothiazin-3(4H)-One

Purity: 98%

Molecular weight: 323.33g/mol

Ref: 54-PC105244

NS6180

CAS: 353262-04-1

NS6180

Purity: ≥95%

Molecular weight: 323.33g/mol

Ref: 54-BUP05290

NS6180

CAS: 353262-04-1

NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.

Formula: C₁₆H₁₂F₃NOS

Purity: 99.83% - ≥95%

Color and Shape: Solid

Molecular weight: 323.33

Ref: TM-T1752

NS-6180

CAS: 353262-04-1

4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one is a novel compound that inhibits the activation of microglia and reduces the Ca2+ concentration in activated microglia. It also has a safety profile and does not affect blood pressure or cause autoimmune diseases. Functional assays show that 4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one inhibits the production of inflammatory cytokines such as IL-6 and TNFα.

Formula: C₁₆H₁₂F₃NOS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 323.33 g/mol

Ref: 3D-FT98361