CAS 353262-04-1

Formula: C16H12F3NOS

InChI: InChI=1S/C16H12F3NOS/c17-16(18,19)12-5-3-4-11(8-12)9-20-13-6-1-2-7-14(13)22-10-15(20)21/h1-8H,9-10H2

InChI key: ZUIJXKLTUFCDGO-UHFFFAOYSA-N

SMILES: C1C(=O)N(C2=CC=CC=C2S1)CC3=CC(=CC=C3)C(F)(F)F

4-[[3-(Trifluoromethyl)phenyl]Methyl]-2H-1,4-Benzothiazin-3(4H)-One

CAS: 353262-04-1

4-[[3-(Trifluoromethyl)phenyl]Methyl]-2H-1,4-Benzothiazin-3(4H)-One

Formula: C₁₆H₁₂F₃NOS

Purity: 98%

Molecular weight: 323.33

Ref: 54-PC105244

NS-6180

CAS: 353262-04-1

Formula: C₁₆H₁₂F₃NOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.3328

Ref: IN-DA00C6GW

NS6180

CAS: 353262-04-1

NS6180

Formula: C₁₆H₁₂F₃NOS

Purity: ≥95%

Molecular weight: 323.33

Ref: 54-BUP05290

NS6180

CAS: 353262-04-1

NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.

Formula: C₁₆H₁₂F₃NOS

Purity: 99.83% - 99.86%

Color and Shape: White Solid

Molecular weight: 323.333

Ref: TM-T1752

NS-6180

CAS: 353262-04-1

4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one is a novel compound that inhibits the activation of microglia and reduces the Ca2+ concentration in activated microglia. It also has a safety profile and does not affect blood pressure or cause autoimmune diseases. Functional assays show that 4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one inhibits the production of inflammatory cytokines such as IL-6 and TNFα.

Formula: C₁₆H₁₂F₃NOS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 323.33 g/mol

Ref: 3D-FT98361

NS6180

CAS: 353262-04-1

4-(3-(Trifluoromethyl)benzyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

Formula: C₁₆H₁₂F₃NOS

Purity: 99%

Molecular weight: 323.33

Ref: IN-DG630666