CAS 354814-19-0

Benzonitrile, 5-amino-2-(trifluoromethyl)-

Description:

Benzonitrile, 5-amino-2-(trifluoromethyl)-, also known by its CAS number 354814-19-0, is an organic compound characterized by the presence of a benzonitrile core with an amino group and a trifluoromethyl group attached to the aromatic ring. This compound typically exhibits a colorless to pale yellow liquid form and is known for its aromatic properties. The amino group (-NH2) contributes to its potential as a building block in organic synthesis, while the trifluoromethyl group (-CF3) enhances its lipophilicity and can influence its reactivity and biological activity. Benzonitrile derivatives are often utilized in pharmaceuticals and agrochemicals due to their ability to participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The presence of both electron-withdrawing and electron-donating groups in its structure can significantly affect its chemical behavior, making it a subject of interest in medicinal chemistry and materials science. Safety data should be consulted for handling and usage, as with all chemical substances.

Formula: C₈H₅F₃N₂

Benzonitrile, 5-amino-2-(trifluoromethyl)-

CAS: 354814-19-0

Formula: C₈H₅F₃N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 186.1339

Ref: IN-DA00I71K

5-Amino-2-(trifluoromethyl)benzonitrile

CAS: 354814-19-0

5-Amino-2-(trifluoromethyl)benzonitrile

Formula: C₈H₅F₃N₂

Purity: ≥95%

Color and Shape: white to off-white crystals/ powder

Molecular weight: 186.13g/mol

Ref: 54-PC908568

5-AMINO-2-(TRIFLUOROMETHYL)BENZONITRILE

CAS: 354814-19-0

Formula: C₈H₅F₃N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 186.137

Ref: 10-F500114

5-Amino-2-(trifluoromethyl)benzonitrile

CAS: 354814-19-0

5-Amino-2-(trifluoromethyl)benzonitrile (5-ATB) is a potent anticancer agent that induces apoptosis in human leukemia cells. It has cytostatic and cytotoxic effects on the cancerous cells, which are mediated by its ability to inhibit DNA synthesis. 5-ATB inhibits the enzyme ribonucleotide reductase, which is required for DNA synthesis, and also causes DNA fragmentation. The antitumor activity of 5-ATB is due to its ability to induce apoptosis in leukemia cells. In addition, 5-ATB has been shown to be effective against breast cancer cells as well as other types of cancer cells.

Formula: C₈H₅F₃N₂

Purity: Min. 95%

Molecular weight: 186.14 g/mol

Ref: 3D-EPA81419