CAS 356068-97-8

Desethyl Sunitinib ((Z)-N-(2-(ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide)

CAS: 356068-97-8

Lactams, nesoi

Formula: C₂₀H₂₃FN₄O₂

Color and Shape: Orange Solid

Molecular weight: 370.1805

Ref: 45-1A05060

N-Desethyl Sunitinib

CAS: 356068-97-8

Formula: C₂₀H₂₃FN₄O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 370.4206

Ref: IN-DA007A8Y

(Z)-N-(2-(Ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

CAS: 356068-97-8

(Z)-N-(2-(Ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

Formula: C₂₀H₂₃FN₄O₂

Purity: 95%+

Molecular weight: 370.42

Ref: 54-PC1032748

N-Desethyl Sunitinib

CAS: 356068-97-8

Formula: C₂₀H₂₃FN₄O₂

Color and Shape: Orange Solid

Molecular weight: 370.43

Ref: 4Z-S-412

N-Desethylsunitinib

CAS: 356068-97-8

Color and Shape: Neat

Ref: 61-FOR3568.06

N-Desethylsunitinib

Controlled Product

CAS: 356068-97-8

Formula: C₂₀H₂₃FN₄O₂

Color and Shape: Yellow-Orange

Molecular weight: 370.42

Ref: 86-MM3568.06

N-Desethyl Sunitinib

CAS: 356068-97-8

N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,

Formula: C₂₀H₂₃FN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.42

Ref: TM-T12145

N-Desethyl sunitinib

CAS: 356068-97-8

N-Desethyl sunitinib is an active metabolite of sunitinib. It has been shown to have antitumor response in experimental models, suggesting that it may be a potential biomarker for renal cell cancer. Sunitinib is used in the treatment of cancers such as renal cell cancer and gastrointestinal stromal tumor. N-Desethyl sunitinib has also been shown to affect drug metabolism through the induction of CYP3A4 and CYP2D6, which can lead to drug interactions. This metabolite is detected in human serum by high performance liquid chromatography with a matrix effect analyzer, but not by LC-MS/MS.

Formula: C₂₀H₂₃FN₄O₂

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 370.42 g/mol

Ref: 3D-FD21182

N-Desethyl Sunitinib

CAS: 356068-97-8

Ref: BE-RMCS226012

N-Desethyl Sunitinib-d4 Maleate

Controlled Product

CAS: 356068-97-8

Applications N-Desethyl Sunitinib-d4 Maleate, is the labeled analogue of N-Desethyl Sunitinib (D289650), a metabolite of Sunitinib (S820000).
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003), Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003), Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004), Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004),

Formula: C₂₀H₁₉D₄FN₄O₂•C₄H₄O₄

Color and Shape: Neat

Molecular weight: 347.4511607

Ref: TR-D289653

N-Desethyl Sunitinib

CAS: 356068-97-8

Formula: C₂₀H₂₃FN₄O₂

Molecular weight: 370.43

Ref: ST-EA-CP-S42022