CAS 35730-78-0

Cynaropicrin

Description:

Cynaropicrin is a natural compound classified as a sesquiterpene lactone, primarily found in artichokes (Cynara scolymus) and other members of the Asteraceae family. It is known for its bitter taste and is often associated with the plant's medicinal properties. The chemical structure of cynaropicrin features a lactone ring, contributing to its biological activity. This compound exhibits various pharmacological effects, including anti-inflammatory, antioxidant, and potential anticancer properties, making it of interest in both food science and medicinal research. Additionally, cynaropicrin has been studied for its role in stimulating appetite and aiding digestion, which aligns with traditional uses of artichokes. Its CAS number, 35730-78-0, is a unique identifier that facilitates the cataloging and study of this compound in scientific literature. Overall, cynaropicrin represents a significant example of how natural products can influence health and nutrition.

Formula: C₁₉H₂₂O₆

InChI: InChI=1S/C19H22O6/c1-8-5-14(24-18(22)9(2)7-20)16-11(4)19(23)25-17(16)15-10(3)13(21)6-12(8)15/h12-17,20-21H,1-7H2/t12-,13-,14-,15-,16+,17+/m0/s1

InChI key: InChIKey=KHSCYOFDKADJDJ-NQLMQOPMSA-N

SMILES: C=C1[C@@]2([C@@]3([C@@]([C@@H](OC(C(CO)=C)=O)CC(=C)[C@@]2(C[C@@H]1O)[H])(C(=C)C(=O)O3)[H])[H])[H]

Synonyms:

• 2-(Hydroxymethyl)-2-propenoic Acid (3aR,4S,6aR,8S,9aR,9bR)-Dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl Ester
• 2-Propenoic acid, 2-(hydroxymethyl)-, (3aR,4S,6aR,8S,9aR,9bR)-dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno(4,5-b)furan-4-yl ester
• 2-Propenoic acid, 2-(hydroxymethyl)-, dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester, [3aR-(3aα,4α,6aα,8β,9aα,9bβ)]-
• 68370-45-6
• Azuleno[4,5-b]furan, 2-propenoic acid deriv.
• Cynaropicrin
• Cynaropikrin
• 2-Hydroxymethylpropenoic acid (3aR,4S,6aβ,9aβ,9bα)-dodecahydro-8α-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester
• CYNAROPICRIN(SH)
• [(3aR,4S,6aR,8S,9aR,9bR)-8-hydroxy-3,6,9-trimethylidene-2-oxo-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] 2-(hydroxymethyl)prop-2-enoate
• 2-methylolacrylic acid [(3aR,4S,6aR,8S,9aR,9bR)-8-hydroxy-2-keto-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] ester

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₉H₂₂O₆

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 346.38

Ref: 11-3820

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin

Purity: ≥95%

Molecular weight: 346.37g/mol

Ref: 54-BUP00309

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin is a sesquiterpene lactone found in artichoke with anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.

Formula: C₁₉H₂₂O₆

Purity: 96.15%

Color and Shape: Solid

Molecular weight: 346.37

Ref: TM-TN1543

Cynaropicrin

CAS: 35730-78-0

Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, and could therefore be applied to prevention of UVB-induced photo aging; it may be a potential anticancer agent against some leukocyte cancer cells such as lymphoma or leukemia, through pro-apoptotic activity. Cynaropicrin shows in vivo activity against Trypanosoma brucei. Cynaropicrin possesses immunomodulatory effects on cytokine release, nitric oxide production and immunosuppressive effects. Cynaropicrin also has anti-inflammatory effects, it may participate in the inflammatory response by inhibiting the production of inflammatory mediators and the proliferation of lymphocytes and its inhibitory effect is mediated through conjugation with sulphydryl groups of target protein(s).

Formula: C₁₉H₂₂O₆

Purity: 95%~99%

Molecular weight: 346.379

Ref: BP-BP0443

Cynaropicrin

CAS: 35730-78-0

Formula: C₁₉H₂₂O₆

Purity: ≥ 97.0%

Color and Shape: White to beige powder

Molecular weight: 346.38

Ref: 7W-GY8068

Cynaropicrin

CAS: 35730-78-0

Lactone

Formula: C₁₉H₂₂O₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 346.38

Ref: 5G-89619

Cynaropicrin - Cynara cardunculus (artichoke)

CAS: 35730-78-0

Cynaropicrin is a sesquiterpene lactone, which is a bioactive compound derived from Cynara cardunculus, commonly known as the artichoke. The source of this compound is primarily the leaves and flowering parts of the plant, which have been traditionally used in herbal medicine. Cynaropicrin exhibits its biological activity through the inhibition of various inflammatory pathways, particularly by modulating the NF-κB signaling pathway, which is crucial in the regulation of immune response and inflammation.

Formula: C₁₉H₂₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 346.37 g/mol

Ref: 3D-XC160151