CAS 35854-46-7

3-phenylimidazo[1,5-a]pyridine

Description:

3-Phenylimidazo[1,5-a]pyridine is a heterocyclic organic compound characterized by its fused imidazole and pyridine rings, with a phenyl group attached at the 3-position of the imidazole ring. This compound typically exhibits a planar structure, which contributes to its potential for π-π stacking interactions, making it interesting for various applications in materials science and medicinal chemistry. It is known for its biological activity, particularly as a potential pharmacophore in drug development, where it may exhibit antitumor or antimicrobial properties. The presence of both nitrogen atoms in the imidazole and pyridine rings can influence its reactivity and interaction with biological targets. Additionally, 3-phenylimidazo[1,5-a]pyridine may show solubility in organic solvents, which is a common characteristic of many heterocyclic compounds. Its unique structure and properties make it a subject of interest in research focused on developing new therapeutic agents and understanding its chemical behavior in various environments.

Formula: C₁₃H₁₀N₂

InChI: InChI=1/C13H10N2/c1-2-6-11(7-3-1)13-14-10-12-8-4-5-9-15(12)13/h1-10H

InChI key: BLGGTXOVNVHSSV-UHFFFAOYSA-N

SMILES: c1ccc(cc1)c1ncc2ccccn12

Synonyms:

• 3-Phenyl-2,3a-diazaindene
• Imidazo[1,5-A]Pyridine, 3-Phenyl-
• 3-Phenylimidazo[1,5-a]pyridine

3-Phenylimidazo[1,5-a]pyridine

CAS: 35854-46-7

Formula: C₁₃H₁₀N₂

Purity: >98.0%(GC)(T)

Color and Shape: Light yellow to Yellow to Green powder to crystal

Molecular weight: 194.24

Ref: 3B-P1838

3-Phenylimidazo[1,5-a]pyridine

CAS: 35854-46-7

3-Phenylimidazo[1,5-a]pyridine

Formula: C₁₃H₁₀N₂

Purity: >98.0%

Molecular weight: 194.24

Ref: 54-OR1079251

3-Phenylimidazo[1,5-a]pyridine

CAS: 35854-46-7

Formula: C₁₃H₁₀N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 194.2319

Ref: IN-DA003JVP

3-Phenylimidazo[1,5-a]pyridine

CAS: 35854-46-7

Purity: ≥98%

Molecular weight: 194.2369995

Ref: 10-F639270

3-Phenylimidazo[1,5-a]pyridine

CAS: 35854-46-7

3-Phenylimidazo[1,5-a]pyridine is a quinoline derivative that is used as an anticancer agent. It inhibits the mitochondrial membrane potential and induces apoptosis in cancer cells. 3-Phenylimidazo[1,5-a]pyridine has also been shown to be effective against cervical cancer cells. The cytotoxic effects of this drug are not due to its DNA binding properties but may be due to its ability to inhibit the synthesis of nitroalkanes from nitrites, which may be carcinogenic. This compound binds to the ring of the quinoline moiety in active site of mitochondrial enzymes such as quinolinate phosphoribosyltransferase (QPRT). This binding prevents the enzyme from catalyzing reactions involving nucleotide biosynthesis, protein synthesis, and cell division.

Formula: C₁₃H₁₀N₂

Purity: Min. 95%

Molecular weight: 194.24 g/mol

Ref: 3D-KBA85446