CAS 358970-97-5

Drinabant

Description:

Drinabant is a synthetic compound that acts as a selective antagonist of the cannabinoid receptor type 1 (CB1). It is primarily studied for its potential therapeutic applications in treating obesity and related metabolic disorders by modulating appetite and energy balance. Drinabant's chemical structure features a unique arrangement of functional groups that contribute to its binding affinity and selectivity for the CB1 receptor. The compound is typically administered in a pharmaceutical context, and its efficacy and safety profile have been evaluated in various clinical trials. As a CB1 antagonist, Drinabant may help counteract the effects of endocannabinoids, which are involved in appetite regulation and fat storage. However, like many pharmacological agents, it may also present side effects, which necessitate careful consideration in its therapeutic use. Overall, Drinabant represents a significant area of research in the field of pharmacology, particularly concerning the endocannabinoid system and its implications for metabolic health.

Formula: C₂₃H₂₀Cl₂F₂N₂O₂S

InChI: InChI=1S/C23H20Cl2F2N2O2S/c1-32(30,31)29(21-11-19(26)10-20(27)12-21)22-13-28(14-22)23(15-2-6-17(24)7-3-15)16-4-8-18(25)9-5-16/h2-12,22-23H,13-14H2,1H3

InChI key: InChIKey=IQQBRKLVEALROM-UHFFFAOYSA-N

SMILES: C(N1CC(N(S(C)(=O)=O)C2=CC(F)=CC(F)=C2)C1)(C3=CC=C(Cl)C=C3)C4=CC=C(Cl)C=C4

Synonyms:

• Ave 1625
• Methanesulfonamide, N-[1-[bis(4-chlorophenyl)methyl]-3-azetidinyl]-N-(3,5-difluorophenyl)-
• N-[1-[Bis(4-chlorophenyl)methyl]-3-azetidinyl]-N-(3,5-difluorophenyl)methanesulfonamide
• N-[1-[Bis(4-chlorophenyl)methyl]azetidin-3-yl]-N-(3,5-difluorophenyl)methanesulfonamide
• Drinabant

Drinabant

CAS: 358970-97-5

Drinabant

Formula: C₂₃H₂₀Cl₂F₂N₂O₂S

Purity: 99.5%

Molecular weight: 497.38

Ref: 54-BUP07257

Drinabant

CAS: 358970-97-5

Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.

Formula: C₂₃H₂₀Cl₂F₂N₂O₂S

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 497.385

Ref: TM-T21861

AVE-1625

CAS: 358970-97-5

Formula: C₂₃H₂₀Cl₂F₂N₂O₂S

Purity: 99.92%

Molecular weight: 497.3849

Ref: IN-DA00C0VQ

AVE 1625

CAS: 358970-97-5

Antagonist of cannabinoid receptor CB1

Formula: C₂₃H₂₀Cl₂F₂N₂O₂S

Purity: Min. 95%

Molecular weight: 497.39 g/mol

Ref: 3D-FD102253