CAS 35906-36-6

Onjisaponin B

Description:

Onjisaponin B is a triterpenoid saponin derived from the root of the plant *Polygala tenuifolia*, commonly known for its traditional medicinal uses. This compound is characterized by its complex structure, which typically includes a steroid-like backbone with sugar moieties attached, contributing to its saponin properties. Onjisaponin B exhibits various biological activities, including anti-inflammatory, neuroprotective, and potential anti-cancer effects, making it of interest in pharmacological research. Its solubility in water is influenced by the glycosidic components, which can enhance its bioavailability. Additionally, Onjisaponin B may interact with cell membranes due to its amphiphilic nature, leading to various physiological effects. The compound's safety profile and therapeutic potential are subjects of ongoing studies, particularly in the context of traditional medicine and modern pharmacotherapy. Overall, Onjisaponin B represents a significant area of interest in natural product chemistry and its applications in health and medicine.

Sinegin 3

CAS: 35906-36-6

Formula: C₇₅H₁₁₂O₃₅

Purity: 98%

Molecular weight: 1573.6708

Ref: IN-DA00CHMC

Onjisaponin B

CAS: 35906-36-6

Formula: C₇₅H₁₁₂O₃₅

Molecular weight: 1573.69

Ref: 7W-GY8133

Onjisaponin B

CAS: 35906-36-6

Onjisaponin B, derived from Radix Polygalae, can enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells.

Formula: C₇₅H₁₁₂O₃₅

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 1573.69

Ref: BP-BP1030

Onjisaponin B

CAS: 35906-36-6

Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-

Formula: C₇₅H₁₁₂O₃₅

Purity: 99.20% - 99.972%

Color and Shape: Solid

Molecular weight: 1573.67

Ref: TM-TN1140

Onjisaponin B

CAS: 35906-36-6

Onjisaponin B is a triterpenoid saponin that has been shown to have anti-angiogenic effects, neuroprotective properties, and autophagy inducing activity. Onjisaponin B has also been shown to inhibit the production of tumor necrosis factor-α (TNF-α) in cultured PC12 cells. The anti-inflammatory effects of this compound may be due to its ability to induce autophagy. This compound induces autophagy by activating the mechanistic target of rapamycin (mTOR) pathway, which leads to the induction of autophagy through the activation of AMP kinase. Onjisaponin B has been found in plants used in traditional Chinese medicine and other Asian countries.

Formula: C₇₅H₁₁₂O₃₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 1,573.67 g/mol

Ref: 3D-FO73797