CAS 3605-01-4

piribedil

Description:

Piribedil is a chemical compound primarily used in the treatment of Parkinson's disease and other movement disorders. It acts as a dopamine agonist, specifically targeting D2 and D3 dopamine receptors, which helps to alleviate symptoms associated with dopamine deficiency. The substance is characterized by its ability to enhance dopaminergic activity in the brain, thus improving motor function and reducing rigidity and tremors. Piribedil is typically administered orally and has a favorable pharmacokinetic profile, allowing for relatively consistent plasma levels. Its chemical structure includes a pyrimidine ring, which contributes to its pharmacological properties. Additionally, piribedil exhibits some neuroprotective effects, making it a subject of interest in research beyond Parkinson's disease. Side effects may include nausea, dizziness, and fatigue, similar to other dopaminergic agents. Overall, piribedil represents a valuable option in the management of Parkinson's disease, particularly for patients who may not respond adequately to other treatments.

Formula: C₁₆H₁₈N₄O₂

InChI: InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2

InChI key: InChIKey=OQDPVLVUJFGPGQ-UHFFFAOYSA-N

SMILES: C(C=1C=C2C(=CC1)OCO2)N3CCN(CC3)C=4N=CC=CN4

Synonyms:

• 1-(2-Pyrimidyl)-4-(3,4-methylenedioxybenzyl)piperazine
• 1-(2-Pyrimidyl)-4-piperonylpiperazine
• 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
• 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine
• 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine Methanesulfonate (1:1)
• 2[4-(1,3-Benzodioxol-5-Ylmethyl)-1-Piperazinyl-]Pyrimidine
• 4-[3,4-(Methylenedioxy)benzyl]-1-(2-pyrimidinyl)piperazine
• Et 495
• Eu 4200
• Piribendyl
• Pronoran
• Pyrimidine, 2-(4-piperonyl-1-piperazinyl)-
• Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-
• Trivastal
• Trivastan
• PIRIBEDIOL
• PIRIBEDIL

Piribedil

CAS: 3605-01-4

Formula: C₁₆H₁₈N₄O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 298.35

Ref: 3B-P2054

2-[4-(2H-1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine

CAS: 3605-01-4

Formula: C₁₆H₁₈N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.3397

Ref: IN-DA0039YE

Piribedil

CAS: 3605-01-4

Piribedil

Formula: C₁₆H₁₈N₄O₂

Purity: ≥98%

Molecular weight: 298.34

Ref: 54-BUP15104

Piribedil

CAS: 3605-01-4

Formula: C₁₆H₁₈N₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 298.35

Ref: 4Z-P-104001

2-(4-(Benzo[D][1,3]Dioxol-5-Ylmethyl)Piperazin-1-Yl)Pyrimidine

CAS: 3605-01-4

2-(4-(Benzo[D][1,3]Dioxol-5-Ylmethyl)Piperazin-1-Yl)Pyrimidine

Formula: C₁₆H₁₈N₄O₂

Purity: 98%

Molecular weight: 298.34

Ref: 54-OR1009742

Piribedil

CAS: 3605-01-4

Formula: C₁₆H₁₈N₄O₂

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 298.34

Ref: 7W-GP9213

Piribedil

CAS: 3605-01-4

Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.

Formula: C₁₆H₁₈N₄O₂

Purity: 99.79% - 99.82%

Color and Shape: Solid

Molecular weight: 298.34

Ref: TM-T3278

Piribedil

Controlled Product

CAS: 3605-01-4

Applications Piribedil is an antiparkisonian agent that acts as a dopamine agonist. Piribedil also displays α2-adrenergic antagonist properties. Piribedil has also been shown to counteract age-related memory impairment by improving memory and attention as well as increasing the velocity of psychomotor reactions and lability of nervous processes.
References Millan, M.J. et al.: J. Pharmacol. Exp. Therap., 297, 876 (2001); Gobert, A. et al.: J. Pharmacol. Exp. Therap., 305, 338 (2003); Bochkarev, V.K. et al.: Zh. Nevrol. Psikhiatr. Im. S.S. Korsakova, 105, 46 (2005);

Formula: C₁₆H₁₈N₄O₂

Color and Shape: Neat

Molecular weight: 298.34

Ref: TR-P508750

2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine

CAS: 3605-01-4

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 298.34600830078125

Ref: 10-F241812

Piribedil

CAS: 3605-01-4

Agonist of D2 and D3 dopamine receptors; anti-parkinson drug

Formula: C₁₆H₁₈N₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 298.34 g/mol

Ref: 3D-FP65134

Piribedil

CAS: 3605-01-4

Formula: C₁₆H₁₈N₄O₂

Molecular weight: 298.35

Ref: ST-EA-CP-P179000