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CAS 3605-01-4

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piribedil

Description:
Piribedil is a chemical compound primarily used in the treatment of Parkinson's disease and other movement disorders. It acts as a dopamine agonist, specifically targeting D2 and D3 dopamine receptors, which helps to alleviate symptoms associated with dopamine deficiency. The substance is characterized by its ability to enhance dopaminergic activity in the brain, thus improving motor function and reducing rigidity and tremors. Piribedil is typically administered orally and has a favorable pharmacokinetic profile, allowing for relatively consistent plasma levels. Its chemical structure includes a pyrimidine ring, which contributes to its pharmacological properties. Additionally, piribedil exhibits some neuroprotective effects, making it a subject of interest in research beyond Parkinson's disease. Side effects may include nausea, dizziness, and fatigue, similar to other dopaminergic agents. Overall, piribedil represents a valuable option in the management of Parkinson's disease, particularly for patients who may not respond adequately to other treatments.
Formula:C16H18N4O2
InChI:InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2
InChI key:InChIKey=OQDPVLVUJFGPGQ-UHFFFAOYSA-N
SMILES:C(C=1C=C2C(=CC1)OCO2)N3CCN(CC3)C=4N=CC=CN4
Synonyms:
  • 1-(2-Pyrimidyl)-4-(3,4-methylenedioxybenzyl)piperazine
  • 1-(2-Pyrimidyl)-4-piperonylpiperazine
  • 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
  • 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine
  • 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine Methanesulfonate (1:1)
  • 2[4-(1,3-Benzodioxol-5-Ylmethyl)-1-Piperazinyl-]Pyrimidine
  • 4-[3,4-(Methylenedioxy)benzyl]-1-(2-pyrimidinyl)piperazine
  • Et 495
  • Eu 4200
  • Piribendyl
  • See more synonyms
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