CAS 36062-04-1

Tetrahydrocurcumin

Description:

Tetrahydrocurcumin is a chemical compound derived from curcumin, the active component of turmeric. It is a diketone with a molecular structure that includes a saturated cyclohexene ring, which distinguishes it from its parent compound, curcumin. Tetrahydrocurcumin is known for its potential antioxidant properties, which may contribute to various health benefits, including anti-inflammatory effects and potential neuroprotective activities. The compound is typically yellow in color and is soluble in organic solvents, while exhibiting limited solubility in water. Its stability is generally higher than that of curcumin, making it a subject of interest in both food and pharmaceutical applications. Research has indicated that tetrahydrocurcumin may have therapeutic potential in various conditions, including cancer and cardiovascular diseases, although further studies are needed to fully understand its mechanisms and efficacy. Overall, tetrahydrocurcumin represents a promising area of study in natural product chemistry and its applications in health and wellness.

Formula: C₂₁H₂₄O₆

InChI: InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3

InChI key: InChIKey=LBTVHXHERHESKG-UHFFFAOYSA-N

SMILES: C(CC(CC(CCC1=CC(OC)=C(O)C=C1)=O)=O)C2=CC(OC)=C(O)C=C2

Synonyms:

• 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
• 3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
• As-Ktc 004
• Hziv 81-2
• NSC 687845
• Sabiwhite
• Tetrahydrocurcumin
• Tetrahydrodiferuloylmethane

Tetrahydrocurcumin

CAS: 36062-04-1

Formula: C₂₁H₂₄O₆

Purity: >95.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 372.42

Ref: 3B-T3587

Tetrahydrocurcumin

CAS: 36062-04-1

Tetrahydrocurcumin

Formula: C₂₁H₂₄O₆

Purity: ≥95%

Molecular weight: 372.41

Ref: 54-BUP00163

Tetrahydro Curcumin (Mixture of Tautomeric Isomers)

CAS: 36062-04-1

Formula: C₂₁H₂₄O₆

Color and Shape: White To Off-White Solid

Molecular weight: 372.42

Ref: 4Z-C-6910

Tetrahydrocurcumin

CAS: 36062-04-1

Formula: C₂₁H₂₄O₆

Purity: ≥ 96.0% (anhydrous basis)

Color and Shape: White to off-white or light-yellow powder

Molecular weight: 372.41

Ref: 7W-GL2375

Tetrahydro-curcumin

CAS: 36062-04-1

Tetrahydro-curcumin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₄O₆

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 372.42

Ref: 11-4747S

Tetrahydrocurcumin

CAS: 36062-04-1

Formula: C₂₁H₂₄O₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 372.417

Ref: BP-BP3386

Tetrahydro Curcumin

Controlled Product

CAS: 36062-04-1

Stability Light Sensitive
Applications Tetrahydro Curcumin is a major metabolite of Curcumin (C838500) that has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress.
References Namareoung, S. et al.: Naun.-Schmied. Arch. Pharmacol.,383, 519 (2011); Kartileksan, K. et al.: J. Func. Foods, 2, 134 (2009);

Formula: C₂₁H₂₄O₆

Color and Shape: Neat

Molecular weight: 372.41

Ref: TR-T293385

Tetrahydrocurcumin

CAS: 36062-04-1

1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione

Formula: C₂₁H₂₄O₆

Purity: 98%

Molecular weight: 372.41

Ref: IN-DG167945

Tetrahydrocurcumin

CAS: 36062-04-1

Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.

Formula: C₂₁H₂₄O₆

Purity: 97.81% - 98.82%

Color and Shape: Yellow Solid

Molecular weight: 372.41

Ref: TM-T3735

Tetrahydro Curcumin-d6 (Mixture of Tautomeric Isomers)

CAS: 36062-04-1

Formula: C₂₁H₁₈D₆O₆

Molecular weight: 378.45

Ref: 4Z-C-6920

Tetrahydrocurcumin

CAS: 36062-04-1

Ketone phenol

Formula: C₂₁H₂₄O₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 372.42

Ref: 5G-82665

Tetrahydro Curcumin

CAS: 36062-04-1

Formula: C₂₁H₂₄O₆

Molecular weight: 372.42

Ref: ST-EA-CP-C147003

Tetrahydro curcumin - Natural

CAS: 36062-04-1

Tetrahydro curcumin is a natural polyphenol found in the roots of Curcuma longa. It has been shown to inhibit the activity of enzymes such as pyrazole ring hydroxylase, which is responsible for the conversion of tetrahydrocurcumin to curcumin. Tetrahydro curcumin also inhibits autophagy, which plays an important role in the development of hepatic steatosis and insulin resistance. Researchers have found that this compound can be used as a potential analytical method for detecting drug transporters. This compound also induces neuronal death and apoptosis pathway activation by inhibiting mitochondrial membrane potential and activation of caspases. Tetrahydro curcumin may also be able to prevent kidney fibrosis by preventing activation of TGF-β1 and Smad3 pathways.

Formula: C₂₁H₂₄O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 372.41 g/mol

Ref: 3D-FT28087

Tetrahydro curcumin, Synthetic

CAS: 36062-04-1

Tetrahydro curcumin is a synthetic analog of curcumin with a pyrazole ring. Tetrahydro curcumin has been shown to inhibit the activity of various enzymes, such as cyclooxygenase and lipoxygenase, which have been implicated in cancer development. This compound also inhibits the activity of drug transporters, thus reducing the concentration of drugs that are transported out of cells and into bloodstream.

Formula: C₂₁H₂₄O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 372.41 g/mol

Ref: 3D-FT146193

Tetrahydrocurcumin

CAS: 36062-04-1

Formula: C₂₁H₂₄O₆

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 372.417

Ref: 10-F078919