CAS 36093-85-3

4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoic acid

Description:

4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoic acid, with the CAS number 36093-85-3, is a chemical compound that belongs to the class of pteridine derivatives. This substance features a benzoic acid moiety linked to a pteridine structure, which is characterized by its bicyclic arrangement containing nitrogen atoms. The presence of amino groups in the pteridine ring contributes to its potential biological activity, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The compound is likely to exhibit properties such as solubility in polar solvents due to the presence of carboxylic acid and amino functional groups, which can also participate in hydrogen bonding. Its structural complexity may influence its reactivity and interaction with biological targets. Additionally, the compound may have implications in research related to cancer treatment or other therapeutic areas, given the role of pteridine derivatives in various biochemical pathways. Proper handling and storage conditions are essential to maintain its stability and efficacy.

Formula: C₁₄H₁₃N₇O₂

InChI: InChI=1/C14H13N7O2/c15-11-10-12(21-14(16)20-11)18-6-9(19-10)5-17-8-3-1-7(2-4-8)13(22)23/h1-4,6,17H,5H2,(H,22,23)(H4,15,16,18,20,21)

InChI key: OSYSFOFKQDNPGP-UHFFFAOYSA-N

SMILES: c1cc(ccc1C(=O)O)NCc1cnc2c(c(N)[nH]c(=N)n2)n1

Synonyms:

• Benzoic Acid, 4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Amino]-
• 4-(N-[2,4-Diamino-6-pteridinylmethyl]-amino)Benzoic acid
• 4-{[(2,4-Diaminopteridin-6-yl)methyl]amino}benzoic acid

4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoic acid

CAS: 36093-85-3

4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoic acid

Purity: 98%

Molecular weight: 311.3049927

Ref: 10-F624518

4-Aminodeoxopteroic Acid

Controlled Product

CAS: 36093-85-3

Applications 4-Aminodeoxopteroic Acid, is an intermediate for the synthesis of Aminopterin (A628850), a folic acid antagonist. They can also be used as precursors for De Novo synthesis of antifolates: A novel class of antimalarials.
References Matherly, L.H., et al.: Cancer Res., 45, 1073 (1985); Nduati, E., et al.: Anti. Age. Chem., 49, 3652 (2005);

Formula: C₁₄H₁₃N₇O₂

Color and Shape: Neat

Molecular weight: 311.3

Ref: TR-A603895